Results 121 to 130 of about 421,141 (266)

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Unified Object Detector With Dynamic Switch Mechanism Based on Deep Learning Advances: A Paradigm-Aware Architecture for Adaptive Detection

IEEE Access
Object detection research has evolved through different architectural paradigms, including two-stage region-based models, one-stage efficiency-focused detectors, and more recent transformer methods, where each performs well in a specific domain but none ...
Oussama Hmidani, El Mehdi Ismaili Alaoui
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Dynamic networks differentiate the language ability of children with cochlear implants. [PDF]

Front Neurosci, 2023
Koirala N, Deroche MLD, Wolfe J, Neumann S, Bien AG, Doan D, Goldbeck M, Muthuraman M, Gracco VL.   +8 more
europepmc   +1 more source

Dynamics in financial networks

Dynamique des réseaux financiers Dynamique des réseaux financiers.
openaire   +2 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

A Novel Temporal Network-Embedding Algorithm for Link Prediction in Dynamic Networks. [PDF]

Entropy (Basel), 2023
Abbas K, Abbasi A, Dong S, Niu L, Chen L, Chen B.   +5 more
europepmc   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Distinguishing between different percolation regimes in noisy dynamic networks with an application to epileptic seizures. [PDF]

PLoS Comput Biol, 2023
Zhu X, Shappell H, Kramer MA, Chu CJ, Kolaczyk ED.   +4 more
europepmc   +1 more source