Results 141 to 150 of about 421,141 (266)

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

A statistical framework for recovering pseudo-dynamic networks from static data. [PDF]

Bioinformatics, 2022
Chen C, Shen B, Ma T, Wang M, Wu R.
europepmc   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

The development of dynamic networks supporting attentional flexibility. [PDF]

Dev Cogn Neurosci
Coleman SC, Rhodes N, Wong SM, Mithani K, Warsi NM, Suresh H, Anagnostou E, Crosbie J, Schachar R, Lerch JP, Taylor MJ, Ibrahim GM.   +11 more
europepmc   +1 more source

Spite is contagious in dynamic networks. [PDF]

Nat Commun, 2021
Fulker Z, Forber P, Smead R, Riedl C.
europepmc   +1 more source

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source

CO₂-responsive terpolymer hydrogels with adjustable dynamic networks for fractured plugging in the reservoir. [PDF]

Sci Rep
Yan Y, Tao Y, Zhou S, Fan Y, Zhang P.
europepmc   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Interfacial Bioengineering of Dynamic Networks Hybrid Hydrogel for Programmed Intervention in Oral Precancerous Epithelial States. [PDF]

Adv Healthc Mater
Zhao X, Zheng A, Zhao Z, Li Q, Wan T, Deng T, Zhang Y, Cao L, Wu L.   +8 more
europepmc   +1 more source

A Cartographic Tool to Predict Disease Risk-associated Pseudo-Dynamic Networks from Tissue-specific Gene Expression. [PDF]

Bio Protoc, 2023
Chen C, Shen B, Zhang L, Yu T, Wang M, Wu R.   +5 more
europepmc   +1 more source