Results 101 to 110 of about 6,062,729 (295)

The Cognitive Virtues of Dynamic Networks

, 2010
For the most part, studies in the network science literature tend to focus on networks whose functional connectivity is largely invariant with respect to some episode of collective information processing.
Sycara, Katia, Huynh, Trung Dong, Braines, Dave, Smart, Paul R, Shadbolt, Nigel   +4 more
core   +1 more source

Networks of respiratory‐muscular coupling in exercise and fatigue in young adults

Physiological Reports
Respiratory and muscular systems must integrate ventilation, oxygen delivery, and muscle activation to meet exercise demands. While decades of research have provided understanding of how these systems function individually, the principles regulating ...
Sergi Garcia‐Retortillo, Javier O. Pinzon Arenas, Óscar Abenza, Hugo F. Posada‐Quintero, Plamen Ch. Ivanov   +4 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

Energy and Spectral Efficiency Analysis for UAV-to-UAV Communication in Dynamic Networks for Smart Cities

Smart Cities
Unmanned Aerial Vehicles (UAVs) are integral to the development of smart city infrastructures, enabling essential services such as real-time surveillance, urban traffic regulation, and cooperative environmental monitoring.
Mfonobong Uko, Sunday Ekpo, Ubong Ukommi, Unwana Iwok, Stephen Alabi   +4 more
doaj   +1 more source

How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome

FEBS Letters, EarlyView.
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini, Freia S. Buus, Benjamin Schuler, Birthe B. Kragelund   +3 more
wiley   +1 more source

Attention-Based Anomaly Detection in Dynamic Network

Big Data Mining and Analytics
Detecting anomalies in dynamic networks is essential for a range of real-world applications, such as social networks and cybersecurity. However, it encounters substantial challenges due to the diverse and ever-evolving nature of these anomalies.
Yiming Zhao, Wenjun Wang, Nannan Wu, Jilei Liu, Ying Sun, Wei Yu, Quannan Zu   +6 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source