Results 81 to 90 of about 421,141 (266)

Public Goods Games on Coevolving Social Network Models

open access: yesFrontiers in Physics, 2020
Public good games are a metaphor for modeling cooperative behavior in groups in the presence of incentives to free ride. In the model presented here agents play a public good game with their neighbors in a social network structure. Agents' decision rules
Marco Tomassini, Alberto Antonioni
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Towards Secure and Efficient Farming Using Self-Regulating Heterogeneous Federated Learning in Dynamic Network Conditions

open access: yesAgriculture
The advancement of precision agriculture increasingly depends on innovative technological solutions that optimize resource utilization and minimize environmental impact.
Sai Puppala, Koushik Sinha
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

A Process-Based Approach to Transtheoretical Clinical Research and Training

open access: yesClinical Psychology in Europe
[Background] The science and practice of psychopathology and psychological intervention of today is more like an island archipelago than it is a single land mass, and connections between different traditions are both limited and fraught with ...
Stefan G. Hofmann, Steven C. Hayes
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

The maximum flow in dynamic networks [PDF]

open access: yesComputer Science Journal of Moldova, 2005
The dynamic maximum flow problem that generalizes the static maximum flow problem is formulated and studied. We consider the problem on a network with capacities depending on time, fixed transit times on the arcs, and a given time horizon.
Maria A. Fonoberova, Dmitrii D. Lozovanu
doaj  

An Enhanced Incremental SVD Algorithm for Change Point Detection in Dynamic Networks

open access: yesIEEE Access, 2018
Change point detection is essential to understand the time-evolving structure of dynamic networks. Recent research shows that a latent semantic indexing (LSI)-based algorithm effectively detects the change points of a dynamic network.
Yongsheng Cheng, Jiang Zhu, Xiaokang Lin
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Home - About - Disclaimer - Privacy