Results 151 to 160 of about 9,974,561 (338)

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

Eslabones Activos | Paisajes Expuestos

open access: yesRevistArquis, 2014
PRESENTACIÓN Este trabajo de investigación aplicada busca implementar mini-proyectos interconectados de manera táctica, para que haya una complementación directa entre los diferentes subsistemas (movilidad, vegetal, vivienda, comercial, educativo ...
Gabriela Soloviy
doaj  

Adapting to asynchronous dynamic networks (extended abstract) [PDF]

open access: bronze, 1992
Baruch Awerbuch   +3 more
openalex   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

open access: yesFEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

Community-Aware Evolution Similarity for Link Prediction in Dynamic Social Networks

open access: yesMathematics
The link prediction problem is a time-evolving model in network science that has simultaneously abetted myriad applications and experienced extensive methodological improvement. Inferring the possibility of emerging links in dynamic social networks, also
Nazim Choudhury
doaj   +1 more source

Dynamic networks differentiate the language ability of children with cochlear implants. [PDF]

open access: yesFront Neurosci, 2023
Koirala N   +8 more
europepmc   +1 more source

Research progress on the metabolic transformation of Shenling Baizhu San under the influence of the gut microbiota

open access: yesAdvanced Chinese Medicine, EarlyView.
Abstract The gut microbiota plays a pivotal role in maintaining host metabolic homeostasis and overall physiological functions. Shenling Baizhu San (SLBZS), a time‐honored classical prescription for tonifying Qi, strengthening the spleen, removing dampness, and arresting diarrhea, has shown broad clinical efficacy in digestive disorders.
Jinlan Di, Xiaochun Zhang
wiley   +1 more source

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