Results 41 to 50 of about 421,141 (266)

Revealing the hidden structure of dynamic ecological networks [PDF]

Royal Society Open Science, 2017
In ecology, recent technological advances and long-term data studies now provide longitudinal interaction data (e.g. between individuals or species). Most often, time is the parameter along which interactions evolve but any other one-dimensional gradient
Vincent Miele, Catherine Matias
doaj   +1 more source

Visualizing the Evolution of Historical Networks Using Small Multiples in Grid Charts

Journal of Historical Network Research, 2022
Historical time presents interesting conceptual problems for network visualization. The manifestations of time in historical network research (HNR) are similarly numerous and distinct. Time in HNR cannot always be reduced to the concept of chronological
Melanie Conroy, Kimmo Elo, Malte Rehbein, Linda von Keyserlinngk-Rehbein   +3 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

AFE-Net: Attention-Guided Feature Enhancement Network for Infrared Small Target Detection

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Infrared small target detection is considerably challenging due to the few pixels in targets, low signal-to-noise ratio, and complex background. In this article, we propose an effective attention-guided feature enhancement network (AFE-Net), which can ...
Keyan Wang, Xueyan Wu, Peicheng Zhou, Zuntian Chen, Rui Zhang, Liyun Yang, Yunsong Li   +6 more
doaj   +1 more source

Sustainable network dynamics [PDF]

Ecological Modelling, 2011
We propose a dynamic graph-theoretic model for ecosystem management as a control over networked system composed of target nodes and unmarked nodes. The network is represented by a complete graph, in which all vertices are connected by a unique edge. Target nodes are attracted by the objective function issued from the ecosystem-based management.
Dragicevic, Arnaud, A., Sinclair-Desgagné, Bernard, B.   +1 more
openaire   +6 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source