Results 41 to 50 of about 101,531 (260)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Investigation of the Road Noise Source Employing an Automatic Noise Monitoring Station

Archives of Acoustics, 2008
The paper presents a pilot investigation of noise source models in two selected localizations in the context of future dynamic noise map creation. The experiments were carried out using the automatic noise monitoring station engineered at the Multimedia
Maciej SZCZODRAK, Andrzej CZYŻEWSKI, Józef KOTUS   +2 more
doaj  

Ordering Protein Contact Matrices

Computational and Structural Biotechnology Journal, 2018
Numerous biophysical approaches provide information about residues spatial proximity in proteins. However, correct assignment of the protein fold from this proximity information is not straightforward if the spatially close protein residues are not ...
Chuan Xu, Guillaume Bouvier, Benjamin Bardiaux, Michael Nilges, Thérèse Malliavin, Abdel Lisser   +5 more
doaj   +1 more source

Open System Model for Quantum Dynamical Maps with Classical Noise and Corresponding Master Equations [PDF]

Open Systems & Information Dynamics, 2017
We show how random unitary dynamics arise from the coupling of an open quantum system to a static environment. Subsequently, we derive a master equation for the reduced system random unitary dynamics and study three specific cases: commuting system and interaction Hamiltonians, the short-time limit, and the Markov approximation.
Chahan M. Kropf, Vyacheslav N. Shatokhin, Andreas Buchleitner   +2 more
openaire   +3 more sources

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Accuracy of the Dynamic Acoustic Map in a Large City Generated by Fixed Monitoring Units

Sensors, 2020
DYNAMAP, a European Life project, aims at giving a real image of the noise generated by vehicular traffic in urban areas developing a dynamic acoustic map based on a limited number of low-cost permanent noise monitoring stations.
Roberto Benocci, Chiara Confalonieri, Hector Eduardo Roman, Fabio Angelini, Giovanni Zambon   +4 more
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

A High-Fidelity Star Map Simulation Method for Airborne All-Time Three-FOV Star Sensor Under Dynamic Conditions

Remote Sensing
To address the lack of reliable test data for evaluating star sensor performance in dynamic airborne environments, this paper presents a high-fidelity star map simulation method for all-time three-Field of View (FOV) star sensors.
Jingsong Zhou, Hui Zhang, Liang Fang, Xiaodong Gao, Kaili Lu, Wei Sun, Rujin Zhao   +6 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source