Results 91 to 100 of about 10,716,551 (348)

The Rayleigh quotient and dynamic programming

International Journal of Mathematics and Mathematical Sciences, 1978
The purpose of this paper is to derive a nonlinear partial differential equation for which λ given by (1.3), is one value of the solution. In Section 2, we derive this equation using a straightforward dynamic programming approach.
Richard Bellman
doaj   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Research on eco-driving strategies for supercapacitor trams

机车电传动, 2022
Focusing on the eco-driving for supercapacitor trams, considering traction/braking characteristics, trip operation time constraint, variable value of slope and power constraints of supercapacitor, a modified dynamic programming method was proposed with ...
ZHANG Huazhi, FU Chengcheng, XIAO Zhuang, WANG Qingyuan, FENG Xiaoyun, HE Bin   +5 more
doaj  

Design of Predictive Controllers by Dynamic Programming and Neural Networks [PDF]

, 2003
This paper proposes a method for the design of predictive controllers for nonlinear systems. The method consists of two phases, a solution phase and a learning phase.
Nagurka, Mark L., Yen, Chen-Wen
core   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Correction to: On the optimization of pit stop strategies via dynamic programming [PDF]

, 2022
Oscar F. Carrasco Heine, Charles Thraves
openalex   +1 more source

A Practitioner's Guide to Bayesian Estimation of Discrete Choice Dynamic Programming Models [PDF]

This paper provides a step-by-step guide to estimating discrete choice dynamic programming (DDP) models using the Bayesian Dynamic Programming algorithm developed by Imai Jain and Ching (2008) (IJC).
Andrew Ching, Masakazu Ishihara, Neelam Jain, Susumu Imai   +3 more
core  

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Dynamic Programming Algorithms in Speech Recognition [PDF]

Informatică economică, 2008
In a system of speech recognition containing words, the recognition requires the comparison between the entry signal of the word and the various words of the dictionary.
Titus Felix FURTUNA
doaj