Results 101 to 110 of about 957,134 (330)
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
A Note on a Rapid Grid Search Method for Solving Dynamic Programming Problems in Economics [PDF]
We introduce a rapid grid search method in solving the dynamic programming problems in economics. Compared to mainstream grid search methods, by using local information of the Bellman equation, this method can significantly increase the efficiency in ...
Hao Zhang, Hui He
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Lifting Sequence Optimization of Luffing Tower Cranes Considering Motion Paths with Dynamic Programming [PDF]
, 2021 Keyi Wu, Borja García de Soto
openalex +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Solving a Production and Inventory Model with a Minimum Lot Size Constrain [PDF]
The paper deals with the analysis of a special dynamic production and inventory model. In this model logical restrictions to fulfill an accepted constant minimal level of the production lot size are incorporated, instead of keeping setup cost in the ...
Okhrin, Irena, Richter, Knut
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COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Minimizing vehicle fuel consumption on hilly roads based on dynamic programming
Advances in Mechanical Engineering, 2017 Vehicle fuel consumption is greatly influenced by roadway gradients and the driver’s driving behavior. To explore the great energy-saving potential of optimizing driver behavior on hilly roads, a novel eco-driving algorithm is defined and formulated ...
Min Zhou, Hui Jin, Feng Ding
doaj +1 more source
Conditional Risk Mappings [PDF]
We introduce an axiomatic definition of a conditional convex risk mapping. By employing the techniques of conjugate duality we derive properties of conditional risk mappings.
Alexander Shapiro, Andrzej Ruszczynski
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Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Yxilon – a Modular Open-Source Statistical Programming Language [PDF]
Statistical research has always been at the edge of available computing power. Huge datasets, e.g in DataMining or Quantitative Finance, and computationally intensive techniques, e.g.
Sigbert Klinke +2 more
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