Results 91 to 100 of about 957,134 (330)
LSTM Time Series Price Prediction - Deterministic Strategy Gradient Dynamic Programming [PDF]
, 2022 Yuxiao Duan, Yuzhuo Dang, Honghui Chen
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Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
From Dynamic Programming to Bynamic Programming
Journal of Mathematical Analysis and Applications, 1993 The author suggests a new sequential optimization method called `bynamic programming', which includes dynamic programming as a special case. The objective function \(g(x,.)\) defined on \(X\times R^{\ell}\) is separable and at the same time nonincreasing or nondecreasing in the second variable for \(x\in X^ -\), \(x\in X^ +\) respectively, where \(X ...
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Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Dynamic Programming Algorithms in Speech Recognition [PDF]
Informatică economică, 2008 In a system of speech recognition containing words, the recognition requires the comparison between the entry signal of the word and the various words of the dictionary.
Titus Felix FURTUNA
doaj
Adaptive Dynamic Programming based Control Scheme for Uncertain Two-Wheel Robots
, 2021 Linh Anh Nguyen
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Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Design of Predictive Controllers by Dynamic Programming and Neural Networks [PDF]
, 2003 This paper proposes a method for the design of predictive controllers for nonlinear systems. The method consists of two phases, a solution phase and a learning phase.
Nagurka, Mark L., Yen, Chen-Wen
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source