Results 71 to 80 of about 957,134 (330)

Quantum Dynamic Programming

open access: yesPhysical Review Letters
32 pages; stronger results than v1, with significant rewriting of the main ...
Jeongrak Son   +3 more
openaire   +3 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Associative Dynamic Programs

open access: yesJournal of Mathematical Analysis and Applications, 1996
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Feedback Generation for Performance Problems in Introductory Programming Assignments

open access: yes, 2014
Providing feedback on programming assignments manually is a tedious, error prone, and time-consuming task. In this paper, we motivate and address the problem of generating feedback on performance aspects in introductory programming assignments.
Gulwani, Sumit   +2 more
core   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Differential Dynamic Programming for time-delayed systems

open access: yes, 2017
Trajectory optimization considers the problem of deciding how to control a dynamical system to move along a trajectory which minimizes some cost function.
Fan, David D., Theodorou, Evangelos A.
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Adaptive control of plug-in hybrid electric vehicles based on energy management strategy and dynamic programming algorithm

open access: yesInternational Journal of Renewable Energy Development
This study mainly analyses the fuel consumption of plug-in hybrid vehicles during operation. A new control method for automobiles based on energy management strategy and dynamic programming algorithm is proposed.
Yuxin Ge
doaj   +1 more source

Linear Quadratic Games with Costly Measurements

open access: yes, 2017
In this work we consider a stochastic linear quadratic two-player game. The state measurements are observed through a switched noiseless communication link. Each player incurs a finite cost every time the link is established to get measurements.
Anastasopoulos, Achilleas   +2 more
core   +1 more source

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