Results 31 to 40 of about 1,370,654 (308)

Dynamic Response Analysis of Parallel Twin Tunnels Under Different Train Loads

open access: yesApplied Sciences
Due to the spatial constraints of underground environments, the spacing between dual-line tunnels in urban metro systems is often limited, leading to potential mutual interference during the operation of trains in closely spaced parallel tunnels. In this
Lin Wu   +3 more
doaj   +1 more source

Slamming induced dynamic response of a floating structure

open access: yes, 2012
Study of the slamming phenomenon is one of the most important branches of the floating structure dynamics. Experimental study of the floating structure dynamics can be very expensive because it requires a long wave flume and a moving model.
Lotfollahi-Yaghin, Mohammad Ali   +2 more
core   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Investigating the Mechanisms and Dynamic Response of Graded Aggregate Mud Pumping Based on the Hybrid DEM-FDM Method

open access: yesBuildings
This study investigated the macro and meso mechanisms of void formation in graded aggregates within high-speed railway subgrades under train loads using a hybrid discrete element–finite difference method (DEM-FDM).
Kang Wang   +7 more
doaj   +1 more source

The Efficiency of Best-Response Dynamics [PDF]

open access: yes, 2017
Best response (BR) dynamics is a natural method by which players proceed toward a pure Nash equilibrium via a local search method. The quality of the equilibrium reached may depend heavily on the order by which players are chosen to perform their best response moves. A {\em deviator rule} $S$ is a method for selecting the next deviating player.
Michal Feldman   +2 more
openaire   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Dynamic Responses of U-Shaped Caverns under Transient Stress Waves in Deep Rock Engineering

open access: yesMathematics
Deep caverns are frequently subjected to transient loading, resulting in different failure characteristics in the surrounding rock compared to those in shallow caverns.
Lisha Liang   +3 more
doaj   +1 more source

A static analysis-based method for estimating the maximum out-of-plane inelastic seismic response of steel arch bridges [PDF]

open access: yes, 2006
This paper presents a method for estimating the maximum inelastic out-of-plane seismic response of upper-deck steel arch bridges. The method employs the equal-energy assumption to predict the maximum response without the need for dynamic response ...
Cetinkaya, Osman Tunc   +2 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

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