Results 51 to 60 of about 9,329,709 (259)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Dynamic Behavior of a Rotationally Restrained Pipe Conveying Gas-Liquid Two-Phase Flow
Journal of Marine Science and EngineeringThis study explores the dynamic behavior of a vertical pipe conveying gas-liquid two-phase flow with rotationally restrained boundaries, employing the generalized integral transform technique (GITT).
Guangming Fu +6 more
doaj +1 more source
Dynamic response of a curved bridge under moving truck load
, 2002 Though static analysis of bridges is well defined, the results are not very realistic. Dynamic analysis will be more realistic if the model can be calibrated.
Brameld, Gerald H. +2 more
core +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Research on Impact Resistance of Steel Frame Beam-Column Structure Under Fire
BuildingsIn this study, the impact resistance of WUF-B steel frame beam–column joints under fire was investigated using ABAQUS finite element software through a sequential thermal–mechanical coupling approach. By integrating a room-temperature impact model with a
Zhi Li, Yu-Tong Feng, Tian-Qi Xue
doaj +1 more source
A static analysis-based method for estimating the maximum out-of-plane inelastic seismic response of steel arch bridges [PDF]
, 2006 This paper presents a method for estimating the maximum inelastic out-of-plane seismic response of upper-deck steel arch bridges. The method employs the equal-energy assumption to predict the maximum response without the need for dynamic response ...
Cetinkaya, Osman Tunc +2 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Challenges in Risk Analysis and Assessment of the Railway Transport Vibration on Buildings
Applied SciencesTraffic-induced vibrations from road and rail systems pose a significant threat to the structural integrity and operational safety of buildings, especially masonry structures located near planned infrastructure such as tunnels.
Filip Pachla +2 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Frontiers in MaterialsThe structural stability of coal seam roof rock mass under dynamic load in engineering practice is directly influenced by the dynamic characteristics of weakly consolidated coal measures rock.
Guodong Shi +4 more
doaj +1 more source