Results 51 to 60 of about 1,370,654 (308)
This study aims to explore the dynamic response of ballastless tracks under various temperatures of the cement-emulsified asphalt (CA) mortar layer and other environmental factors.
Yunqing Chen +3 more
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Silt soil is widely distributed in coastal, river, and lacustrine sedimentary zones, characterized by high water content, low bearing capacity, high compressibility, and low permeability, representing a typical bulk solid waste.
Chenyu Zhu +5 more
doaj +1 more source
Nonlinear dynamic response of beam and its application in nanomechanical resonator
Nonlinear dynamic response of nanomechanical resonator is of very important characteristics in its application. Two categories of the tension-dominant and curvature-dominant nonlinearities are analyzed. The dynamic nonlinearity of four beam structures of
Liu Y +4 more
core +1 more source
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Thermocouple Sensor Response in Hot Airstream
The response of a temperature sensor in a gas stream depends on several heat transfer phenomena. The temperature of the thermocouple’s hot junction in the hot stream is lower than the measured temperature, which causes a measurement error.
Jacek Pieniazek
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Dynamic Behavior of a Rotationally Restrained Pipe Conveying Gas-Liquid Two-Phase Flow
This study explores the dynamic behavior of a vertical pipe conveying gas-liquid two-phase flow with rotationally restrained boundaries, employing the generalized integral transform technique (GITT).
Guangming Fu +6 more
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Research on Impact Resistance of Steel Frame Beam-Column Structure Under Fire
In this study, the impact resistance of WUF-B steel frame beam–column joints under fire was investigated using ABAQUS finite element software through a sequential thermal–mechanical coupling approach. By integrating a room-temperature impact model with a
Zhi Li, Yu-Tong Feng, Tian-Qi Xue
doaj +1 more source

