Results 41 to 50 of about 1,167,602 (264)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Dynamic Response Analysis of Ballastless Tracks Considering the Temperature-Dependent Viscoelasticity of Cement-Emulsified Asphalt Mortar Based on a Vehicle–Track–Subgrade Coupled Model

Lubricants
This study aims to explore the dynamic response of ballastless tracks under various temperatures of the cement-emulsified asphalt (CA) mortar layer and other environmental factors.
Yunqing Chen, Bing Wu, Linquan Yao, Xianglong Su   +3 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Optimization ratios and multi factor service adaptability of cement-GGBFS stabilized silt in pavement structures

Frontiers in Materials
Silt soil is widely distributed in coastal, river, and lacustrine sedimentary zones, characterized by high water content, low bearing capacity, high compressibility, and low permeability, representing a typical bulk solid waste.
Chenyu Zhu, Dianqiu Yang, Bingquan Song, Yujin Wang, Yunfeng Hu, Hengzhen Wu   +5 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Thermocouple Sensor Response in Hot Airstream

Sensors
The response of a temperature sensor in a gas stream depends on several heat transfer phenomena. The temperature of the thermocouple’s hot junction in the hot stream is lower than the measured temperature, which causes a measurement error.
Jacek Pieniazek
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Dynamic Behavior of a Rotationally Restrained Pipe Conveying Gas-Liquid Two-Phase Flow

Journal of Marine Science and Engineering
This study explores the dynamic behavior of a vertical pipe conveying gas-liquid two-phase flow with rotationally restrained boundaries, employing the generalized integral transform technique (GITT).
Guangming Fu, Huilin Jiao, Aixia Zhang, Xiao Wang, Boying Wang, Baojiang Sun, Jian Su   +6 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Research on Impact Resistance of Steel Frame Beam-Column Structure Under Fire

Buildings
In this study, the impact resistance of WUF-B steel frame beam–column joints under fire was investigated using ABAQUS finite element software through a sequential thermal–mechanical coupling approach. By integrating a room-temperature impact model with a
Zhi Li, Yu-Tong Feng, Tian-Qi Xue
doaj   +1 more source