Results 41 to 50 of about 8,893,345 (301)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Interactive dynamic response for games [PDF]

Proceedings of the 2007 ACM SIGGRAPH symposium on Video games, 2007
Dynamic response is a technique for employing a physical reaction to an animated character. The technique utilizes a database of reactions as example motions to transition to following a dynamic simulation of an interaction. The search for the example to follow has been the stumbling block for bringing such a system into realtime applications and in ...
Victor B. Zordan, Adriano Macchietto, Jose Medina, Marc Soriano, Chun-Chih Wu   +4 more
openaire   +2 more sources

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Experimental and Analytical Study on Multiscale Cushioning and Energy Absorption of Aluminum Foam at Different Strain Rates

Applied Sciences
In this research, the compressive behavior of closed-cell aluminum foam was examined across a broad strain rate spectrum, spanning from 0.005 s⁻1 to 2000 s⁻1.
Qianzhi Qiu, Hongtao Wang, Wentian Ma
doaj   +1 more source

Forced response of shrouded blades with a coupled static/dynamic approach [PDF]

, 2011
A coupled static-dynamic method is proposed and applied to bladed disks with shrouds, in order to calculate the nonlinear forced response in presence of friction damping in the frequency domain.
Zucca, Stefano, Gulisano, Andrea, Firrone, Christian Maria   +2 more
core  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Dynamic Response Analysis of Ballastless Tracks Considering the Temperature-Dependent Viscoelasticity of Cement-Emulsified Asphalt Mortar Based on a Vehicle–Track–Subgrade Coupled Model

Lubricants
This study aims to explore the dynamic response of ballastless tracks under various temperatures of the cement-emulsified asphalt (CA) mortar layer and other environmental factors.
Yunqing Chen, Bing Wu, Linquan Yao, Xianglong Su   +3 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Optimization ratios and multi factor service adaptability of cement-GGBFS stabilized silt in pavement structures

Frontiers in Materials
Silt soil is widely distributed in coastal, river, and lacustrine sedimentary zones, characterized by high water content, low bearing capacity, high compressibility, and low permeability, representing a typical bulk solid waste.
Chenyu Zhu, Dianqiu Yang, Bingquan Song, Yujin Wang, Yunfeng Hu, Hengzhen Wu   +5 more
doaj   +1 more source