Results 61 to 70 of about 3,958,786 (306)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
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Research on Impact Resistance of Steel Frame Beam-Column Structure Under Fire
BuildingsIn this study, the impact resistance of WUF-B steel frame beam–column joints under fire was investigated using ABAQUS finite element software through a sequential thermal–mechanical coupling approach. By integrating a room-temperature impact model with a
Zhi Li, Yu-Tong Feng, Tian-Qi Xue
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The Unsteady, Dynamic Characterization of Hydraulic Systems with Emphasis on Cavitation and Turbomachines [PDF]
, 1978 The ability to analyze and model the unsteady, dynamic response of hydraulic systems has arisen from the need for operational stability, flexibility and controlled transient behavior.
Brennen, Christopher
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
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Challenges in Risk Analysis and Assessment of the Railway Transport Vibration on Buildings
Applied SciencesTraffic-induced vibrations from road and rail systems pose a significant threat to the structural integrity and operational safety of buildings, especially masonry structures located near planned infrastructure such as tunnels.
Filip Pachla +2 more
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FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
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Frontiers in MaterialsThe structural stability of coal seam roof rock mass under dynamic load in engineering practice is directly influenced by the dynamic characteristics of weakly consolidated coal measures rock.
Guodong Shi +4 more
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Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
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Applied SciencesChina has witnessed extensive construction of underground powerhouses for pumped storage power stations. With the continuous increase in unit capacity, vibration problems have become particularly pronounced.
Junhao Gao +9 more
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The low-noise optimisation method for gearbox in consideration of operating conditions [PDF]
, 2014 This paper presents a comprehensive procedure to calculate the steady dynamic response and the noise radiation generated from a stepping-down gearbox.
Kang, J, Sun, W, Tao, Q, Zhou, J
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