Results 81 to 90 of about 1,370,654 (308)
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Shenzhen Daxue xuebao. Ligong banIn the process of blasting excavation of the later excavated tunnel, it is crucial to ensure the safety of blasting vibration in the first excavated tunnel.
HUANG Chuansheng +5 more
doaj +1 more source
Parameter sensitivity study of dynamic response for jack-ups by FEM analysis
, 2016 Jack-up platforms will generally behave as highly dynamic systems because of the structure flexibility. The environmental forces acting on these jack-ups will therefore induce significant dynamic response.
Nie, Wenjun +6 more
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Dynamic Response Analysis of Solar Array of a Satellite
, 2017 The dynamic response analysis to simulate the complicated working condition can ensure the high reliability of space products' design. In this paper, we focus on the solar array of a satellite, and gain equivalent mechanical parameters of its ...
Wang W(王巍) +3 more
core
Safe dynamic design of structures. [PDF]
, 2000 The Design of structures under dynamic loading is a demanding subject in safety of engineering design since conventional static failure criteria are unable to deal with structures under transient loading.
Moatamedi, Mojtaba, Moatamedi, M.
core
Dynamic response of a curved bridge under moving truck load
, 2002 Though static analysis of bridges is well defined, the results are not very realistic. Dynamic analysis will be more realistic if the model can be calibrated.
Brameld, Gerald H. +2 more
core +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
IEEE Open Journal of Industry ApplicationsWith the recent proliferation in penetration levels of converter-based grid-connected wind turbine systems, a decrease in grid strength has been observed.
Ryno Gerber, Maarten Jan Kamper
doaj +1 more source