Results 91 to 100 of about 9,329,709 (259)

Hydrodynamic Performance and Motion Response of a Novel Deep-Water TLP Floating Offshore Wind Turbine

Journal of Marine Science and Engineering
The deployment of floating offshore wind turbines (FOWTs) in deep, typhoon-prone waters like the South China Sea requires platforms with exceptional stability.
Ronghua Zhu, Zongyuan Lai, Chunlong Li, Haiping Qian, Huaqi Yuan, Yingchun Xie, Ke Sun   +6 more
doaj   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source

Nonlinear Dynamic Response of Tension Leg Platform

, 2006
Tension Leg Platform (TLP) is a typical compliant offshore structure for oil exploitation in deep water. Most of the existing mathematical models for analyzing the dynamic response of TLP are based on explicit or implicit assumptions that displacements ...
Zeng XH(曾晓辉), Liu Y(刘阳), Wu YX(吴应湘), 曾晓辉, Shen XP(沈晓鹏)   +4 more
core   +2 more sources

Analysis of Stress Distribution Law and Dynamic Response of Deep Water Test String

Shiyou jixie, 2020
To study the stress distribution and the influence of internal pressure fluctuations on the dynamic response parameters of deep water test string under different working conditions, the calculation formulas of the axial force, axial stress, radial stress
Tang Xiandi, Sun Qiaolei, Li Zhong, Feng Ding, Wang Erjun, Meng Wenbo, Yan Bangchuan   +6 more
doaj  

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Influence of Soil Plugging on Dynamic Soil Response During Simulated Pipe Pile Driving Model Test in Sands

Applied Sciences
The squeezing effect and strike-induced vibration generated by pile driving pose a threat to adjacent structures. To mitigate the squeezing effect, open-ended pipe piles were implemented. However, this type of pile brings a degree of soil-plugging effect,
Songchao Lin, Ye Lu, Chong Zhao
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Dynamic Response and Lubrication Performance of Spur Gear Pair Under Time-Varying Rotation Speeds

Lubricants
The rotation speed directly influences the vibration and lubrication behaviors of gear pairs, but studying the effects of time-varying rotation speeds during their operation poses substantial challenges. The present work proposed an approach to analyzing
Jiaxing Pei, Yuanyuan Tian, Hongjuan Hou, Yourui Tao, Miaojie Wu, Zhigang Guan   +5 more
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source