Results 51 to 60 of about 65,605 (245)

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Quantifying the Influence of Fault Geometry via Mesh Morphing With Applications to Earthquake Dynamic Rupture and Thermal Models of Subduction

Geochemistry, Geophysics, Geosystems
Subsurface geometries, such as faults and subducting slab interfaces, are often poorly constrained, yet they exert first‐order control on key geophysical processes, including subduction zone thermal structure and earthquake rupture dynamics.
Gabrielle M. Hobson, Dave A. May, Alice‐Agnes Gabriel   +2 more
doaj   +1 more source

Dynamic rupture of metal sheet subjected to laser irradiation and tangential subsonic airflow

Theoretical and Applied Mechanics Letters, 2018
: To reproduce the premature rupture process of metal sheet subjected to laser irradiation with subsonic airflow, which is an interesting phenomenon observed in the experiments given by Lawrence Livermore National Laboratory, a coupled numerical model ...
Xiaodong Xing, Te Ma, Ruixing Wang, Chenyu Cao, Hongwei Song, Chenguang Huang   +5 more
doaj   +1 more source

The 2016 Menyuan Earthquake: The Largest Self‐Arrested Crustal Earthquake Ever Observed

Geophysical Research Letters, 2023
The 2016 Mw 5.9 Menyuan earthquake occurred near the Haiyuan fault system in the northeastern Tibetan plateau. Although some kinematic properties of this event have been investigated, more dynamic properties still need to be clarified.
Duyuan Xu, Wenzheng Gong, Zhenguo Zhang, Jiankuan Xu, Houyun Yu, Xiaofei Chen   +5 more
doaj   +1 more source

Development of a Prediction Model for Progression Risk in High‐Grade Gliomas Based on Habitat Radiomics and Pathomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate the value of constructing models based on habitat radiomics and pathomics for predicting the risk of progression in high‐grade gliomas. Methods This study conducted a retrospective analysis of preoperative magnetic resonance (MR) images and pathological sections from 72 patients diagnosed with high‐grade gliomas (52 ...
Yuchen Zhu, Yuxi Gong, Weilin Xu, Xingjian Sun, Gefei Jiang, Lei Qiu, Kexin Shi, Mengxing Wu, Yinjiao Fei, Jinling Yuan, Jinyan Luo, Yurong Li, Yuandong Cao, Minhong Pan, Shu Zhou   +14 more
wiley   +1 more source

Partial ruptures governed by the complex interplay between geodetic slip deficit, rigidity, and pore fluid pressure in 3D Cascadia dynamic rupture simulations

Seismica
Physics-based dynamic rupture simulations are valuable for assessing the seismic hazard in the Cascadia subduction zone (CSZ), but require assumptions about fault stress and material properties.
Jonatan Glehman, Alice Gabriel, Thomas Ulrich, Marlon Ramos, Yihe Huang, Eric Lindsey   +5 more
doaj   +1 more source

Dueling dynamics of low-angle normal fault rupture with splay faulting and off-fault damage

Nature Communications, 2023
Despite a lack of modern large earthquakes on shallowly dipping normal faults, Holocene Mw > 7 low-angle normal fault (LANF ...
J. Biemiller, A.-A. Gabriel, T. Ulrich
doaj   +1 more source

Bistable Mechanisms 3D Printing for Mechanically Programmable Vibration Control

Advanced Engineering Materials, EarlyView.
This work introduces a 3D‐printed bistable mechanism integrated into tuned mass dampers (TMDs) for mechanically adaptive passive vibration suppression. Through optimized geometry, the bistable design provides adaptable vibration reduction across a broad range of scenarios, achieving effective vibration mitigation without complex controls or external ...
Ali Zolfagharian, Frédéric Demoly, Mohammad Lakhi, Bernard Rolfe, Mahdi Bodaghi   +4 more
wiley   +1 more source

Harnessing Fungal Biowelding for Constructing Mycelium‐Engineered Materials

Advanced Engineering Materials, EarlyView.
Mycelium‐bound composites (MBCs) offer low‐carbon alternatives for construction, yet interfacial bonding remains a critical challenge. This review examines fungal biowelding as a biocompatible adhesive, elucidating mycelium‐mediated interfacial mechanisms and their role in material assembly. Strategies to optimize biowelding are discussed, highlighting
Xue Brenda Bai, Xinrui Sarah Niu, Zhao Qin   +2 more
wiley   +1 more source

Role of Weak Materials in Earthquake Rupture Dynamics [PDF]

Scientific Reports, 2019
AbstractWeak materials in seismic slip zones are important in studies of earthquake mechanics. For instance, the exceptionally large slip during the 2011 Tohoku-Oki earthquake has been attributed to the presence of smectite in the fault zone. However, weak fault rocks cannot accumulate large amounts of elastic strain, which is thought to counter their ...
Tetsuro Hirono, Kenichi Tsuda, Shunya Kaneki   +2 more
openaire   +2 more sources