Results 111 to 120 of about 393,113 (294)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Control of parallelized bioreactors I: dynamic scheduling software for efficient bioprocess management in high-throughput systems. [PDF]

Bioprocess Biosyst Eng, 2022
Bromig L, von den Eichen N, Weuster-Botz D.   +2 more
europepmc   +1 more source

rDLB: A Novel Approach for Robust Dynamic Load Balancing of Scientific Applications with Parallel Independent Tasks

, 2019
Scientific applications often contain large and computationally intensive parallel loops. Dynamic loop self scheduling (DLS) is used to achieve a balanced load execution of such applications on high performance computing (HPC) systems.
Cavelan, Aurelien, Ciorba, Florina M., Mohammed, Ali   +2 more
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Analysis of Multi-Path Scheduling Network Model for Intelligent Transportation

Dianxin kexue, 2014
In the field of intelligent transportation, vehicle scheduling is a complex issue with multi-path, multi-types of vehicles and multi-destination. In this process, some time-varying attributes and dynamic indicators have a direct impact on the scheduling ...
Weiyang Qin
doaj   +2 more sources

An optimized two‐phase demand‐responsive transit scheduling model considering dynamic demand

IET Intelligent Transport Systems
Demand‐responsive transit has gradually attracted attention in recent years for its flexibility, efficiency, and ability to meet the diverse travel demands of passengers.
Cui‐Ying Song, He‐Ling Wang, Lu Chen, Xue‐Qin Niu   +3 more
doaj   +1 more source

A Dynamic Scheduling Method Combining Iterative Optimization and Deep Reinforcement Learning to Solve Sudden Disturbance Events in a Flexible Manufacturing Process

Mathematics
Unpredictable sudden disturbances such as machine failure, processing time lag, and order changes increase the deviation between actual production and the planned schedule, seriously affecting production efficiency. This phenomenon is particularly severe
Jun Yan, Tianzuo Zhao, Tao Zhang, Hongyan Chu, Congbin Yang, Yueze Zhang   +5 more
doaj   +1 more source

Dynamic Scheduling of Contextually Categorised Internet of Things Services in Fog Computing Environment. [PDF]

Sensors (Basel), 2022
Krivic P, Kusek M, Cavrak I, Skocir P.
europepmc   +1 more source

Fuzzy Feedback Scheduling of Resource-Constrained Embedded Control Systems

, 2008
The quality of control (QoC) of a resource-constrained embedded control system may be jeopardized in dynamic environments with variable workload. This gives rise to the increasing demand of co-design of control and scheduling.
Dong, Jinxiang, Sun, Youxian, Tade, Moses, Tian, Yu-Chu, Xia, Feng   +4 more
core   +2 more sources

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source