Results 91 to 100 of about 3,378,292 (300)

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Learning based dynamic approach to job-shop scheduling

open access: yes, 2001
Dynamic selection of scheduling rules during real operations has been recognized as a promising approach to the scheduling of the production. This paper studies the dynamic job-shop scheduling and presents a fuzzy logic based learning approach ...
Yu HB(于海斌), Liang W(梁炜)
core  

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Task-Degradation Aware Adaptive Dynamic Scheduling for Priority-Based Automotive Cyber-Physical Systems

open access: yesIEEE Access
The advancement of autonomous driving technology presents significant challenges to automotive cyber-physical systems (ACPS) due to the dynamic and random nature of task releases.
Kaiyu Zhao   +4 more
doaj   +1 more source

Pattern driven dynamic scheduling approach using reinforcement learning

open access: yes, 2009
Production scheduling is critical for manufacturing system. Dispatching rules are usually applied dynamically to schedule the job in the dynamic job-shop. The paper presents an adaptive iterative scheduling algorithm that operates dynamically to schedule
Wei YZ(魏英姿)   +3 more
core  

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

open access: yesFEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda   +2 more
wiley   +1 more source

Crew Scheduling for Netherlands Railways: "destination: customer" [PDF]

open access: yes
: In this paper we describe the use of a set covering model with additional constraints for scheduling train drivers and conductors for the Dutch railway operator NS Reizigers.
Fischetti, M., Kroon, L.G.
core  

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Dynamic Reallocation Problems in Scheduling

open access: yesCoRR, 2015
In this paper we look at the problem of scheduling tasks on a single-processor system, where each task requires unit time and must be scheduled within a certain time window, and each task can be added to or removed from the system at any time. On each operation, the system is allowed to reschedule any tasks, but the goal is to minimize the number of ...
Wei Quan Lim   +2 more
openaire   +2 more sources

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

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