Results 91 to 100 of about 3,230,934 (299)
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Contract net based scheduling approach using interactive bidding for dynamic job shop scheduling
, 2007 Dynamic scheduling should take into account machine scheduling in that flexible manufacturing system can provide alternative processing routes to produce the same product.
Li, Donglai +3 more
core
Application of velocity-based gain-scheduling to lateral auto-pilot design for an agile missile [PDF]
, 2001 In this paper a modern gain-scheduling methodology is proposed which exploits recently developed velocity-based techniques to resolve many of the deficiencies of classical gain-scheduling approaches (restriction to near equilibrium operation, to slow ...
Tsourdos, A. +3 more
core +3 more sources
IEEE AccessThe advancement of autonomous driving technology presents significant challenges to automotive cyber-physical systems (ACPS) due to the dynamic and random nature of task releases.
Kaiyu Zhao +4 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Power efficient dynamic resource scheduling algorithms for LTE [PDF]
, 2010 This paper presents a link level analysis of the rate and energy efficiency performance of the LTE downlink considering the unitary codebook based precoding scheme.
Beh, KC +9 more
core +1 more source
Dynamic Reallocation Problems in Scheduling
CoRR, 2015 In this paper we look at the problem of scheduling tasks on a single-processor system, where each task requires unit time and must be scheduled within a certain time window, and each task can be added to or removed from the system at any time. On each operation, the system is allowed to reschedule any tasks, but the goal is to minimize the number of ...
Wei Quan Lim +2 more
openaire +2 more sources
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source