Results 91 to 100 of about 393,113 (294)
Optimal Algorithms for Scheduling under Time-of-Use Tariffs [PDF]
, 2018 We consider a natural generalization of classical scheduling problems in which using a time unit for processing a job causes some time-dependent cost which must be paid in addition to the standard scheduling cost.
Chen, Lin +4 more
core +1 more source
Throughput Optimal Scheduling with Dynamic Channel Feedback
, 2012 It is well known that opportunistic scheduling algorithms are throughput optimal under full knowledge of channel and network conditions. However, these algorithms achieve a hypothetical achievable rate region which does not take into account the overhead
Alpcan, Tansu +6 more
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
The Impact of Data Replicatino on Job Scheduling Performance in Hierarchical data Grid
, 2010 In data-intensive applications data transfer is a primary cause of job execution delay. Data access time depends on bandwidth. The major bottleneck to supporting fast data access in Grids is the high latencies of Wide Area Networks and Internet ...
Abdi, Somayeh +2 more
core +2 more sources
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Complexity of Scheduling Charging in the Smart Grid
, 2017 In the smart grid, the intent is to use flexibility in demand, both to balance demand and supply as well as to resolve potential congestion. A first prominent example of such flexible demand is the charging of electric vehicles, which do not necessarily ...
Albert, Michael +2 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
AerospaceThe number of real-time dynamic satellite observation missions has been rapidly increasing recently, while little attention has been paid to the dynamic mission-scheduling problem.
Hai Li +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source