Results 101 to 110 of about 61,394 (313)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
A linear programming-based method for job shop scheduling [PDF]
, 2012 We present a decomposition heuristic for a large class of job shop scheduling problems. This heuristic utilizes information from the linear programming formulation of the associated optimal timing problem to solve subproblems, can be used for any ...
Bülbül, Kerem, Kaminsky, Philip
core +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Dynamic Scheduling in Inpatient Nursing
International Journal of Automation Technology, 2009 To shorten the notoriously long waits for service in hospitals in Japan and to improve efficiency, we propose a scheduling algorithm with a 2-layer local search based on simulated annealing -- permutating (switching) (i) tasks among nurses and (ii) subtasks on each nurse.
Mingang Cheng +4 more
openaire +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
AerospaceThe number of real-time dynamic satellite observation missions has been rapidly increasing recently, while little attention has been paid to the dynamic mission-scheduling problem.
Hai Li +6 more
doaj +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Study on dynamic scheduling method of airport refueling vehicles based on DQN
Xibei Gongye Daxue XuebaoAiming at the low utilization rate of airport refueling vehicles and long solution time of exact algorithm caused by the uncertainty of actual flight time, a deep Q network dynamic scheduling method for refueling vehicles combining with the multi ...
CHEN Weixing, LI Yebo
doaj +1 more source
Application of velocity-based gain-scheduling to lateral auto-pilot design for an agile missile
, 2001 In this paper a modern gain-scheduling methodology is proposed which exploits recently developed velocity-based techniques to resolve many of the deficiencies of classical gain-scheduling approaches (restriction to near equilibrium operation, to slow ...
Tsourdos, A. +3 more
core +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source