Results 81 to 90 of about 3,230,934 (299)

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Optimal Dynamic Scheduling of Electric Vehicles in a Parking Lot Using Particle Swarm Optimization and Shuffled Frog Leaping Algorithm

Energies, 2020
In this paper, the optimal dynamic scheduling of electric vehicles (EVs) in a parking lot (PL) is proposed to minimize the charging cost. In static scheduling, the PL operator can make the optimal scheduling if the demand, arrival, and departure time of ...
George S. Fernandez, Vijayakumar Krishnasamy, Selvakumar Kuppusamy, Jagabar S. Ali, Ziad M. Ali, Adel El-Shahat, Shady H. E. Abdel Aleem   +6 more
doaj   +1 more source

Dynamic scheduling of aircraft landings [PDF]

European Journal of Operational Research, 2017
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Bennell, JA, Mesgarpour, M, Potts, CN
openaire   +6 more sources

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

A solution approach for dynamic vehicle and crew scheduling [PDF]

In this paper, we discuss the dynamic vehicle and crew schedulingproblem and we propose a solution approach consisting of solving asequence of optimization problems.
Wagelmans, A.P.M., Huisman, D.
core  

An Ensemble of Heuristic Adaptive Contract Net Protocol for Efficient Dynamic Data Relay Satellite Scheduling Problem

Aerospace
Task scheduling in data relay satellite networks (DRSNs) is subject to dynamic disruptions such as resource failures, sudden surges in task demands, and variations in service duration requirements.
Manyi Liu, Guohua Wu, Yi Gu, Qizhang Luo
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Dynamic scheduling strategy and algorithm for mixed batch scheduling in vacuum freeze-dried fruit processes

Production Engineering Archives
Vacuum freeze-dried fruit processes consisting of heating and holding are modelled as a mixed batch scheduling with the objective of minimizing the makespan. The jobs differ from each other in job family, size, weight and ready time. The batch processing
Huang JinDian, Hong YingHan, Lin KeYe
doaj   +1 more source