Results 81 to 90 of about 3,378,292 (300)
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Dynamic scheduling of aircraft landings [PDF]
European Journal of Operational Research, 2017 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Bennell, JA, Mesgarpour, M, Potts, CN
openaire +6 more sources
A solution approach for dynamic vehicle and crew scheduling [PDF]
In this paper, we discuss the dynamic vehicle and crew schedulingproblem and we propose a solution approach consisting of solving asequence of optimization problems.
Wagelmans, A.P.M., Huisman, D.
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FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
AerospaceTask scheduling in data relay satellite networks (DRSNs) is subject to dynamic disruptions such as resource failures, sudden surges in task demands, and variations in service duration requirements.
Manyi Liu, Guohua Wu, Yi Gu, Qizhang Luo
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Production Engineering ArchivesVacuum freeze-dried fruit processes consisting of heating and holding are modelled as a mixed batch scheduling with the objective of minimizing the makespan. The jobs differ from each other in job family, size, weight and ready time. The batch processing
Huang JinDian, Hong YingHan, Lin KeYe
doaj +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Contract net based scheduling approach using interactive bidding for dynamic job shop scheduling
, 2007 Dynamic scheduling should take into account machine scheduling in that flexible manufacturing system can provide alternative processing routes to produce the same product.
Li, Donglai +3 more
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