Results 61 to 70 of about 393,113 (294)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Hybrid static/dynamic scheduling for already optimized dense matrix factorization [PDF]

, 2011
We present the use of a hybrid static/dynamic scheduling strategy of the task dependency graph for direct methods used in dense numerical linear algebra. This strategy provides a balance of data locality, load balance, and low dequeue overhead.
Donfack, Simplice, Grigori, Laura, Gropp, William D., Kale, Vivek   +3 more
core   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Dynamic scheduling of process groups

Concurrency: Practice and Experience, 1998
Summary: We introduce the concept of temporal locality of communication for process groups and a hierarchical decision model for dynamic scheduling of process groups. Empirical evidence suggests that, once a member of a process group starts to communicate with other processes in the group, it will continue to do so, while an independent process will ...
Wang, Kuei Yu, Marinescu, Dan C., Carbunar, Octavian F.   +2 more
openaire   +5 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Automated generation of dispatching rules for the green unrelated machines scheduling problem

Complex & Intelligent Systems
The concept of green scheduling, which deals with the environmental impact of the scheduling process, is becoming increasingly important due to growing environmental concerns.
Nikolina Frid, Marko Ɖurasević, Francisco Javier Gil-Gala   +2 more
doaj   +1 more source

A family of heuristics for agent-based elastic Cloud bag-of-tasks concurrent scheduling [PDF]

, 2013
The scheduling and execution of bag-of-tasks applications (BoTs) in Clouds is performed on sets of virtualized Cloud resources that start being exhausted right after their allocation disregarding whether tasks are being executed. In addition, BoTs may be
Gutierrez-Garcia, J. Octavio, Sim, Kwang Mong   +1 more
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Application of simulated annealing algorithm in multi-objective cooperative scheduling of load and storage of source network for load side of new power system

Energy Informatics
To improve the adaptability of grid load collaborative scheduling, a multi-objective collaborative scheduling method based on a simulated annealing algorithm for the load storage of grid loads on the load side of a new power system is proposed. Local bus
Xinming Wang, Huayang Liang, Xiaobo Jia, Shihui Li, Shengyang Kang, Yan Gao   +5 more
doaj   +1 more source