Control of parallelized bioreactors I: dynamic scheduling software for efficient bioprocess management in high-throughput systems. [PDF]
Bioprocess Biosyst Eng, 2022 Bromig L +2 more
europepmc +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
An optimized two‐phase demand‐responsive transit scheduling model considering dynamic demand
IET Intelligent Transport SystemsDemand‐responsive transit has gradually attracted attention in recent years for its flexibility, efficiency, and ability to meet the diverse travel demands of passengers.
Cui‐Ying Song +3 more
doaj +1 more source
Future Internet, 2019 Volunteer computing (VC) is a distributed computing paradigm, which provides unlimited computing resources in the form of donated idle resources for many large-scale scientific computing applications.
Ling Xu +3 more
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Dynamic Scheduling of Contextually Categorised Internet of Things Services in Fog Computing Environment. [PDF]
Sensors (Basel), 2022 Krivic P, Kusek M, Cavrak I, Skocir P.
europepmc +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Attention-Shared Multi-Agent Actor-Critic-Based Deep Reinforcement Learning Approach for Mobile Charging Dynamic Scheduling in Wireless Rechargeable Sensor Networks. [PDF]
Entropy (Basel), 2022 Jiang C +6 more
europepmc +1 more source
Dynamic Scheduling of a Semiconductor Production Line Based on a Composite Rule Set
, 2017 Various factors and constraints should be considered when developing a manufacturing production schedule, and such a schedule is often based on rules. This paper develops a composite dispatching rule based on heuristic rules that comprehensively consider
Yumin Ma +3 more
semanticscholar +1 more source
A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy
Molecular Oncology, EarlyView.Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti +3 more
wiley +1 more source