Results 51 to 60 of about 32,732 (244)

Automated generation of dispatching rules for the green unrelated machines scheduling problem

Complex & Intelligent Systems
The concept of green scheduling, which deals with the environmental impact of the scheduling process, is becoming increasingly important due to growing environmental concerns.
Nikolina Frid, Marko Ɖurasević, Francisco Javier Gil-Gala   +2 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Application of simulated annealing algorithm in multi-objective cooperative scheduling of load and storage of source network for load side of new power system

Energy Informatics
To improve the adaptability of grid load collaborative scheduling, a multi-objective collaborative scheduling method based on a simulated annealing algorithm for the load storage of grid loads on the load side of a new power system is proposed. Local bus
Xinming Wang, Huayang Liang, Xiaobo Jia, Shihui Li, Shengyang Kang, Yan Gao   +5 more
doaj   +1 more source

Dynamic Multi Threshold Priority Packet Scheduling Algorithms

MATEC Web of Conferences, 2016
Packet scheduling algorithms are developed in order to use shared transmission resources efficiently. Various application packets such as real and non-real time packets might have different QoS requirements and traditional scheduling algorithms might be ...
Dag Tamer, Uzungenc Sezer
doaj   +1 more source

Optimal Dynamic Scheduling of Electric Vehicles in a Parking Lot Using Particle Swarm Optimization and Shuffled Frog Leaping Algorithm

Energies, 2020
In this paper, the optimal dynamic scheduling of electric vehicles (EVs) in a parking lot (PL) is proposed to minimize the charging cost. In static scheduling, the PL operator can make the optimal scheduling if the demand, arrival, and departure time of ...
George S. Fernandez, Vijayakumar Krishnasamy, Selvakumar Kuppusamy, Jagabar S. Ali, Ziad M. Ali, Adel El-Shahat, Shady H. E. Abdel Aleem   +6 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Dynamic scheduling for heterogeneous Desktop Grids [PDF]

Journal of Parallel and Distributed Computing, 2008
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Al-Azzoni, Issam, Down, Douglas G.
openaire   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source