Results 71 to 80 of about 3,221,773 (299)

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Dynamic prediction of gas concentration based on time series

open access: yesGong-kuang zidonghua, 2018
Existing gas concentration prediction methods could only achieve static gas concentration prediction, could not update with accumulation of gas data, as a result, the prediction results were not timeliness.
GUO Siwen, TAO Yufan, LI Chao
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Associative memory scheme for genetic algorithms in dynamic environments [PDF]

open access: yes, 2006
Copyright @ Springer-Verlag Berlin Heidelberg 2006.In recent years dynamic optimization problems have attracted a growing interest from the community of genetic algorithms with several approaches developed to address these problems, of which the memory ...
A. Karaman   +3 more
core   +4 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Mistuned Dynamic Response Analysis of Series Mechanism

open access: yesJixie chuandong, 2016
The series periodic mechanism has mistuned dynamic response and peculiarity. The series mechanism model is set up based on theory and method of multi- body dynamics.
Yu Linchong, Lin Zhishu, Lin Xingyan
doaj  

Functional Principal Component Analysis for Non-stationary Dynamic Time Series [PDF]

open access: yes, 2018
Motivated by a highly dynamic hydrological high-frequency time series, we propose time-varying Functional Principal Component Analysis (FPCA) as a novel approach for the analysis of non-stationary Functional Time Series (FTS) in the frequency domain ...
Elayouty, Amira   +3 more
core  

Using Dynamics to Analyse Time Series

open access: yes, 2017
We present a review of recent work to analyze time series in a robust manner using Wasserstein distances which are numerical costs of an optimal transportation problem. Given a time series, the long-term behavior of the dynamical system represented by the time series is reconstructed by Takens delay embedding method.
openaire   +2 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Dynamic parameters for Brazilian financial time series

open access: yesEconomia Aplicada, 2002
In this study we analyse a Brazilian stock index called IBOVESPA using techniques from dynamical systems theory and stochastic processes. We discuss the Lyapunov exponent, the correlation dimension, the LempelZiv complexity, the Hurst exponent and the ...
Gerson Francisco   +2 more
doaj  

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