Results 81 to 90 of about 7,569,463 (308)

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Decomposing the dynamics in time series data with spectral analysis

Frontline Learning Research
Many educational and social phenomena are dynamic and change over time. To study such phenomena, intensive longitudinal data and time-series analyses are essential.
Helena J. M. Pennings, Monika H. Donker
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

CONSIDERATIONS REGARDING THE EVOLUTION OF GROSS DOMESTIC EXPENDITURE ON R&D (GERD) IN ROMANIA AND EU COUNTRIES. PART II – DYNAMIC RHYTHMS [PDF]

Journal of Defense Resources Management
In this paper we have analyzed the evolution of Gross Domestic Expenditure on R&D (GERD) in Romania and EU countries on the last ten years with the available data (2013-2022) provided by the EUROSTAT database.
Cristina ANTONOAIE
doaj  

Similarity evaluation of rocket time series data based on radian features

Dianzi Jishu Yingyong
Evaluating the similarity of rocket time series data is one of the main tasks in rocket time series data analysis. Dynamic time warping (DTW) is the most representative similarity measurement algorithm, but due to its susceptibility to pathological ...
Zeng Teng, Xu Haizhou, Li Linfeng, Zhou Gan, Meng Linggang   +4 more
doaj   +1 more source

TSEE: an elastic embedding method to visualize the dynamic gene expression patterns of time series single-cell RNA sequencing data

BMC Genomics, 2019
Background Time series single-cell RNA sequencing (scRNA-seq) data are emerging. However, the analysis of time series scRNA-seq data could be compromised by 1) distortion created by assorted sources of data collection and generation across time samples ...
Shaokun An, Liang Ma, Lin Wan
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Dynamic Performance of Concrete Considering Initial Stresses and Creep

Железобетонные конструкции
In accidental design situations, the loading mode of reinforced concrete structures includes two typical stages such as long-term deformation under constant or slowly varying load and dynamic impact.
S. Yu. Savin, M. Z. Sharipov
doaj   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Research on Correlation Analysis for Multidimensional Time Series Based on the Evolution Synchronization of Network Topology

Mathematics
We apply the inherent dynamic consistency of a dynamic system as the basis for correlation analysis among different variables in a system. We use network analysis to measure the correlativity of multiple variables, find the interdependence between ...
Hongduo Cao, Ying Li
doaj   +1 more source