Results 81 to 90 of about 3,221,773 (299)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Fuzzy Dynamic Reliability Model of Dependent Series Mechanical Systems

open access: yesAdvances in Mechanical Engineering, 2013
Conventional static fuzzy reliability models cannot be directly extended for dynamic reliability analysis of mechanical systems, which consist of correlative components with strength degradation, due to the difficulties in describing the strength ...
Peng Gao, Shaoze Yan
doaj   +1 more source

Estimation of Dynamic Networks for High-Dimensional Nonstationary Time Series

open access: yesEntropy, 2019
This paper is concerned with the estimation of time-varying networks for high-dimensional nonstationary time series. Two types of dynamic behaviors are considered: structural breaks (i.e., abrupt change points) and smooth changes.
Mengyu Xu, Xiaohui Chen, Wei Biao Wu
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Similarity evaluation of rocket time series data based on radian features

open access: yesDianzi Jishu Yingyong
Evaluating the similarity of rocket time series data is one of the main tasks in rocket time series data analysis. Dynamic time warping (DTW) is the most representative similarity measurement algorithm, but due to its susceptibility to pathological ...
Zeng Teng   +4 more
doaj   +1 more source

Puiseux series dynamics of quadratic rational maps [PDF]

open access: yesIsrael Journal of Mathematics, 2014
We give a complete description for the dynamics of quadratic rational maps with coefficients in the completion of the field of formal Puiseux series.
openaire   +6 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Dynamic Bayesian Predictive Synthesis in Time Series Forecasting

open access: yes, 2017
We discuss model and forecast combination in time series forecasting. A foundational Bayesian perspective based on agent opinion analysis theory defines a new framework for density forecast combination, and encompasses several existing forecast pooling ...
McAlinn, Kenichiro, West, Mike
core  

Modelling of heat emitters embedded within third order lumped parameter building envelope model [PDF]

open access: yes, 2012
A dynamic modelling approach for heat emitters embedded within an existing third order lumped parameter building envelope model is reported in this work.
Edge, Jerry   +4 more
core  

Nonlinear Dynamics Time Series Analysis [PDF]

open access: yes, 2009
This chapter contains sections titled: Introduction Dynamical Systems Theory Time Series Analysis Discussion This chapter contains sections titled: References ...
openaire   +1 more source

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