Results 41 to 50 of about 5,132,694 (221)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Opportunism in Spectrum Sharing for Beyond 5G With Sub-6 GHz: A Concept and Its Application to Duplexing

IEEE Access, 2020
With the envisioned massive connectivity era, one of the challenges for 5G/Beyond 5G (B5G) wireless systems will be handling the unprecedented spectrum crunch.
Soo-Min Kim, Jeemin Kim, Han Cha, Min Soo Sim, Jinho Choi, Seung-Woo Ko, Chan-Byoung Chae, Seong-Lyun Kim   +7 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Heuristically Accelerated Reinforcement Learning for Dynamic Secondary Spectrum Sharing

IEEE Access, 2015
This paper examines how flexible cellular system architectures and efficient spectrum management techniques can be used to play a key role in accommodating the exponentially increasing demand for mobile data capacity in the near future. The efficiency of
Nils Morozs, Tim Clarke, David Grace
doaj   +1 more source

5G Technology: Towards Dynamic Spectrum Sharing Using Cognitive Radio Networks

IEEE Access, 2020
The explosive popularity of small-cell and Internet of Everything devices has tremendously increased traffic loads. This increase has revolutionised the current network into 5G technology, which demands increased capacity, high data rate and ultra-low ...
W. S. H. M. W. Ahmad, N. A. M. Radzi, F. S. Samidi, A. Ismail, F. Abdullah, M. Z. Jamaludin, M. N. Zakaria   +6 more
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Anonymous Dynamic Spectrum Access and Sharing Mechanisms for the CBRS Band

IEEE Access, 2021
The Federal Communications Commission (FCC) has released the 3.5 GHz (3550-3700 MHz) band, termed Citizens Broadband Radio Service (CBRS), for shared broadband use between incumbent federal and secondary users through dynamic and opportunistic spectrum ...
Mohamed Grissa, Attila Altay Yavuz, Bechir Hamdaoui, Chittibabu Tirupathi   +3 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

FEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

Spectrum sharing through distributed coordination in dynamic spectrum access networks [PDF]

Wireless Communications and Mobile Computing, 2007
AbstractSpectrum sharing in Open Spectrum systems is a challenging problem, particularly since users experience dynamic spectrum availabilities that vary over time and location. In the absence of any centralized infrastructure, users coordinate their spectrum usage to support fair access of spectrum and avoid interference.
Jun Zhao, Haitao Zheng, Guang-Hua Yang
openaire   +4 more sources