Results 111 to 120 of about 2,169,888 (325)

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

open access: yesMolecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau   +9 more
wiley   +1 more source

Decomposition-aggregation stability analysis [PDF]

open access: yes
This report presents the development and description of the decomposition aggregation approach to stability investigations of high dimension mathematical models of dynamic systems.
Cuk, S. M.   +2 more
core   +1 more source

Stability of Skew Dynamical Systems

open access: yesJournal of Differential Equations, 1996
Let \(M\) be a compact differential manifold and \(T\) be a compact metric space. The paper considers a dynamical system induced by a homeomorphism \(f:M \times T \to M \times T\) of the form \(f(x,t) = (\Psi (x,t),\;V(t))\), where \(\Psi (x,t)\) is a diffeomorphism for fixed \(t\), and \(V: T \to T\) is an almost periodic homeomorphism.
Xiujun Zhang, Kenneth R. Meyer
openaire   +3 more sources

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

open access: yesMolecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach   +8 more
wiley   +1 more source

Experimental Study on Small-Scale Shake Table Testing of Cable-Stiffened Single-Layer Spherical Latticed Shell

open access: yesBuildings
The cable-stiffened single-layer latticed shell is an innovative structural design that achieves a perfect balance between lightweight and stability by combining cables and a latticed shell. However, the study on dynamic response and failure mechanism of
Ying Zhao   +7 more
doaj   +1 more source

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

open access: yesMolecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche   +8 more
wiley   +1 more source

DYNAMIC MATRIX GAMES AND THEIR MIXED EXTENSION

open access: yesВестник Кемеровского государственного университета, 2014
A new class of game models, called dynamic matrix games (DMG) was introduced in [2] as a generalization of the classical matrix games considering the time factor.
N. N. Danilov
doaj  

Dual-Task Elderly Gait of Prospective Fallers and Non-Fallers: A Wearable-Sensor Based Analysis

open access: yesSensors, 2018
Wearable sensors could facilitate point of care, clinically feasible assessments of dynamic stability and associated fall risk through an assessment of single-task (ST) and dual-task (DT) walking.
Jennifer Howcroft   +3 more
doaj   +1 more source

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