Results 121 to 130 of about 4,042,218 (312)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Health monitoring system of steel structure of rapid quantitative loading statio
Gong-kuang zidonghua, 2013 The paper analyzed static strain measurement principle and dynamic acceleration measurement principle of steel structure of rapid quantitative loading station, and introduced arrangement of measuring points, choosing of measuring time and working ...
CHEN Ying, CHANG Jie-yun, ZHANG Heng
doaj
Performance and test section flow characteristics of the National Full-Scale Aerodynamics Complex 80- by 120-Foot Wind Tunnel [PDF]
Results from the performance and test section flow calibration of the 80- by 120-Foot Wind Tunnel are presented. Measurements indicating the 80- by 120-ft test section flow quality were obtained throughout the tunnel operational envelope and for ...
Zell, Peter T.
core +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
CrystalsThe effect of parameters such as angle of attack, flow velocity, and electrolyte concentration (saline solution) on the extent of material degradation, as well as the morphology and depth of corrosion pits in an airfoil made of 2024-T3 aluminum alloy ...
Gilberto Daniel Conejo Magaña +4 more
doaj +1 more source
On protection of Freedom's solar dynamic radiator from the orbital debris environment. Part 2: Further testing and analyses [PDF]
Presented here are results of a test program undertaken to further define the response of the solar dynamic radiator to hypervelocity impact (HVI). Tests were conducted on representative radiator panels (under ambient, nonoperating conditions) over a ...
Christiansen, Eric L. +2 more
core +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
A Test for Autocorrelation in Dynamic Panel Data Models [PDF]
This paper presents an autocorrelation test that is applicable to dynamic panel data models with serially correlated errors. Our residual-based GMM t-test (hereafter: t-test) differs from the m2 and Sargan's over-identifying restriction (hereafter ...
Hosung Jung
core
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source