Results 41 to 50 of about 1,135,072 (266)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

A Wide-Range Displacement Sensor Based on Plastic Fiber Macro-Bend Coupling

open access: yesSensors, 2017
This paper proposes the strategy of fabricating an all fiber wide-range displacement sensor based on the macro-bend coupling effect which causes power transmission between two twisted bending plastic optical fibers (POF), where the coupling power changes
Jia Liu   +7 more
doaj   +1 more source

THE ASSESSMENT OF THE POLLUTANT EMISSION FROM THE SELF IGNITION ENGINE IN ITS DIFFERENT OPERATING STATES [PDF]

open access: yesArchives of Transport, 2014
Paper presents the results of pollutant emission tests from the self ignition engine in various states of its operation. Engine operating states were obtained on the engine test stand.
Zdisław Chłopek
doaj   +1 more source

The Effect of Welded Splice with Predetermined Gap of Concrete Spun Pile on The Response of Low Strain Integrity Test

open access: yesCivil Engineering Dimension, 2022
This paper presents the velocity wave of concrete spun piles with welded splice. The stress wave velocity was recorded using Pile Integrity Test. Two specimens were prepared in the experiment.
Gogot Setyo Budi, Levin S. Tanaya
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

An experimental study of the fracture morphology of marble under dynamic loading

open access: yesShuiwen dizhi gongcheng dizhi, 2022
To investigate the fracture morphology characteristics of marble under dynamic loading, the dynamic compression and splitting tests of rock samples under different impact velocities are carried out using the split-Hopkinson pressure bar.
Weixiang WANG   +3 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

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