Results 61 to 70 of about 1,197,302 (267)

Experimental Calculation of Added Masses for the Accurate Construction of Airship Flight Models

open access: yesAerospace
In recent years, interest in airships for cargo transport and stratospheric platforms has increased, necessitating accurate dynamic modeling for stability analysis, autopilot design, and mission planning, specifically through the calculation of stability
Deibi López   +4 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Testing dynamical models of vision

open access: yesVision Research, 2011
Most models of vision focus either on the spatial or temporal aspects of visual processing and neglect the other component. A variety of studies have shown, however, that spatial and temporal processing cannot easily be separated. The shine-through effect has proven to be a sensitive tool to study spatio-temporal processing.
Rüter, Johannes   +3 more
openaire   +3 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Biomechanical comparison of using traditional and 3D-printed titanium alloy anatomical assembly thin anterior plating under three patellar fracture conditions

open access: yesVirtual and Physical Prototyping
This study attempted to understand the biomechanics of using 3D-printed anatomical assembly thin bone plate (AATBP) and anterior star-shaped plating (ASP) under different patellar fractures.
Chi-Yang Liao   +4 more
doaj   +1 more source

Cyclic fatigue resistance of new and used ProTaper universal and ProTaper next nickel-titanium rotary instruments

open access: yesSaudi Endodontic Journal, 2018
Aim: This study aims to compare the cyclic fatigue resistance of new and used ProTaper Universal (PTU) and ProTaper Next (PTN) rotary nickel-titanium systems using artificial canals.
Neslihan Büşra Keskin   +3 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Experimental Study on Dynamic Effects of a Long-span Railway Continuous Beam Bridge

open access: yesApplied Sciences, 2018
Studies on impact effects of trains on the railway bridge are important for ensuring the reliability of bridge and the safety of train operation. This paper presents an experimental study on the dynamic effects of moving trains on a long-span railway ...
Hongye Gou   +4 more
doaj   +1 more source

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