Results 81 to 90 of about 4,042,218 (312)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Virtual and Physical PrototypingThis study attempted to understand the biomechanics of using 3D-printed anatomical assembly thin bone plate (AATBP) and anterior star-shaped plating (ASP) under different patellar fractures.
Chi-Yang Liao +4 more
doaj +1 more source
Transparent Dynamic reconfiguration for CORBA [PDF]
, 2001 Distributed systems with high availability requirements have to support some form of dynamic reconfiguration. This means that they must provide the ability to be maintained or upgraded without being taken off-line.
Almeida, João Paulo A. +3 more
core +3 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Practical considerations regarding results from static and dynamic load testing of bridges [PDF]
, 2019 Bridge tests are a helpful tool for bridge assessment and evaluation. Both in the case of a static and dynamic load testing, each element of the test: the load selection and application, the creation of a numerical model to follow the progress of the ...
Casas Rius, Joan Ramon, Olaszek, Piotr
core +3 more sources
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Analysis on the synergistic variation law of pile refreezing process and bearing capacity based on high-strain dynamic test method. [PDF]
Sci Rep, 2023 Yu D, Cao Y, Zhao Q.
europepmc +1 more source
Dynamic test results for the CASES ground experiment [PDF]
The Controls, Astrophysics, and Structures Experiment in Space (CASES) Ground Test Facility (GTF) has been developed at Marshall Space Flight Center (MSFC) to provide a facility for the investigation of Controls/Structures Interaction (CSI) phenomena, to
Bukley, Angelia P. +2 more
core +1 more source
Dominance learning in diploid genetic algorithms for dynamic optimization problems [PDF]
, 2006 Copyright @ 2006 YangThis paper proposes an adaptive dominance mechanism for diploidy genetic algorithms in dynamic environments. In this scheme, the genotype to phenotype mapping in each gene locus is controlled by a dominance probability, which is ...
Yang, S
core +1 more source