Results 111 to 120 of about 334,309 (266)

Dynamical Modeling as a Tool for Inferring Causation. [PDF]

Am J Epidemiol, 2022
Ackley SF, Lessler J, Glymour MM.
europepmc   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Uncovering personalized glucose responses and circadian rhythms from multiple wearable biosensors with Bayesian dynamical modeling. [PDF]

Cell Rep Methods, 2023
Phillips NE, Collet TH, Naef F.
europepmc   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Editorial: Compound Climate Extremes in the Present and Future Climates: Machine Learning, Statistical Methods and Dynamical Modelling

Frontiers in Earth Science, 2021
Wei Zhang, Hiroyuki Murakami, Hiroyuki Murakami, Abdou Khouakhi, Ming Luo, Ming Luo   +5 more
doaj   +1 more source

Parallel Dynamical Systems over Graphs and Related Topics: A Survey

Journal of Applied Mathematics, 2015
In discrete processes, as computational or genetic ones, there are many entities and each entity has a state at a given time. The update of states of the entities constitutes an evolution in time of the system, that is, a discrete dynamical system.
Juan A. Aledo, Silvia Martinez, Jose C. Valverde   +2 more
doaj   +1 more source

Dynamical modeling of proliferative-invasive plasticity and IFNγ signaling in melanoma reveals mechanisms of PD-L1 expression heterogeneity. [PDF]

J Immunother Cancer, 2023
Subhadarshini S, Sahoo S, Debnath S, Somarelli JA, Jolly MK.   +4 more
europepmc   +1 more source

AND-NOT logic framework for steady state analysis of Boolean network models

, 2012
Finite dynamical systems (e.g. Boolean networks and logical models) have been used in modeling biological systems to focus attention on the qualitative features of the system, such as the wiring diagram.
Buschur, Kristina, Hamershock, Rose, Kniss, Ariel, Laubenbacher, Reinhard, Veliz-Cuba, Alan, Wolff, Esther   +5 more
core  

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Predictive dynamical modeling and stability of the equilibria in a discrete fractional difference COVID-19 epidemic model. [PDF]

Results Phys, 2023
Chu YM, Rashid S, Akdemir AO, Khalid A, Baleanu D, Al-Sinan BR, Elzibar OAI.   +6 more
europepmc   +1 more source