Results 131 to 140 of about 334,309 (266)
MODELING OF PLANT TISSUE GROWTH AND DEVELOPMENT WITH L-SYSTEMS
Вавиловский журнал генетики и селекции, 2014 An introduction to modeling of dynamical systems possessing dynamical structures with L-systems is given. Application of L systems is illustrated by models of plant tissue growth and control of state variable distribution in the growing tissue.
U. S. Zubairova +2 more
doaj
Nonlinear dynamical modeling of neural activity using volterra series with GA-enhanced particle swarm optimization algorithm. [PDF]
Cogn Neurodyn, 2023 Chang S +6 more
europepmc +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Dynamical Modeling of the Core Gene Network Controlling Transition to Flowering in Pisum sativum. [PDF]
Front Genet, 2021 Pavlinova P, Samsonova MG, Gursky VV.
europepmc +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Modeling Tidal Disruptions with Dynamical Tides
The Astrophysical JournalTidal disruption events (TDEs) occur when stars pass close enough to supermassive black holes to be torn apart by tidal forces. Traditionally, these events are studied with computationally intensive hydrodynamical simulations. In this paper, we present a
Zihan Zhou +3 more
doaj +1 more source
Dynamical Modeling of Optogenetic Circuits in Yeast for Metabolic Engineering Applications. [PDF]
ACS Synth Biol, 2021 Lovelett RJ +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source