Results 71 to 80 of about 58,720 (307)

Basic Ideas to Approach Metastability in Probabilistic Cellular Automata [PDF]

open access: yes, 2018
Cellular Automata are discrete-time dynamical systems on a spatially extended discrete space, which provide paradigmatic examples of nonlinear phenomena.
Cirillo, E.M.N.   +7 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Multiregression Dynamic Models

open access: yesJournal of the Royal Statistical Society Series B: Statistical Methodology, 1993
SUMMARY Multiregression dynamic models are defined to preserve certain conditional independence structures over time across a multivariate time series. They are non-Gaussian and yet they can often be updated in closed form. The first two moments of their one-step-ahead forecast distribution can be easily calculated. Furthermore, they can
Queen, Catriona M., Smith, Jim Q.
openaire   +2 more sources

Message spreading modeling from the perspective of social psychology, differential equation dynamics, and deep learning technique

open access: yesNonlinear Analysis
To gain a deeper understanding of the characteristics of message spreading, it is crucial to explore various methods of modeling this phenomenon. Given that message spreading is significantly influenced by social media, we propose a modified spreading ...
Yuntao Li, Yan Zhang, Jiazhe Lin
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

An approach to logical-mathematical computer modeling of linear and nonlinear dynamical systems [PDF]

open access: yesE3S Web of Conferences
The paper deals with the problem of modeling linear and nonlinear dynamical systems using information technologies and programming. The processes of modeling, synthesis and inference of solutions to problems are considered, and the possibility of their ...
Zaytsev Anatoly   +2 more
doaj   +1 more source

A Discrete Mathematical Modeling of the Influence of Alcohol Treatment Centers on the Drinking Dynamics Using Optimal Control

open access: yesJournal of Applied Mathematics, 2020
In this paper, we propose a discrete mathematical model that describes the interaction between the classes of drinkers, namely, potential drinkers P, moderate drinkers M, heavy drinkers H, poor heavy drinkers Tp, rich heavy drinkers Tr, and quitters of ...
Bouchaib Khajji   +4 more
doaj   +1 more source

A Dynamic Model of Commutes [PDF]

open access: yesEnvironment and Planning A: Economy and Space, 2005
This paper studies the interaction between commuting, job mobility, and housing mobility. Many conventional models assume that the employment location has priority over the residential location and that the latter is adapted to the former. This implies that commutes which start with a job change will often be short lived because of a change in ...
Jan Rouwendal, Arno van der Vlist
openaire   +8 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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