Results 81 to 90 of about 58,720 (307)

Mathematical Modeling and Analysis of an Alcohol Drinking Model with the Influence of Alcohol Treatment Centers

International Journal of Mathematics and Mathematical Sciences, 2020
In this paper, we present a continuous mathematical model PMHTrTpQ of alcohol drinking with the influence of private and public addiction treatment centers.
Bouchaib Khajji, Abderrahim Labzai, Omar Balatif, Mostafa Rachik   +3 more
doaj   +1 more source

Dynamical modeling and morphological analysis

, 1998
After a historical sketch of the dynamical hypothesis, we stress that it is a functionalist hypothesis. We then tackle the point of a dynamical approach to constituent structures and emphasize that dynamical modeling must be coupled with morphological
Jean Petitot
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Improving dynamical climate predictions with machine learning: insights from a twin experiment framework [PDF]

Nonlinear Processes in Geophysics
Systematic errors in dynamical climate models remain a significant challenge to accurate climate predictions, particularly when modeling the nonlinear coupling between the atmosphere and ocean.
Z. He, Z. He, Z. He, J. Brajard, Y. Wang, X. Wang, X. Wang, Z. Shen, Z. Shen   +8 more
doaj   +1 more source

A statistical-dynamical modeling approach for the simulation of local paleo proxy records using GCM output [PDF]

, 1998
Recent proxy data obtained from ice core measurements, dendrochronology and valley glaciers provide important information on the evolution of the regional or local climate.
Åkesson, O, Reichert, B. K., Reichert, B., Bengtsson, Lennart, Bengtsson, L., Åkesson, O.   +5 more
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Flow-Field Modeling and Mixing Mechanisms of the Twin-Shaft Mixers Based on LBM–LES Coupling

Machines
In modern industrial systems, twin-shaft mixers are key units for efficient mixing and reactions; their performance directly affects product quality, production cycle, and energy consumption across the chemical, pharmaceutical, food, and lithium-battery ...
Wentao Zhao, Jianxiong Ye, Lin Li, Gaoan Zheng   +3 more
doaj   +1 more source

Mathematical Modeling and Optimal Control Strategy for a Discrete Time Drug Consumption Model

Discrete Dynamics in Nature and Society, 2020
The aim of this paper is to study and investigate the optimal control strategy of a discrete mathematical model of drug consumption. The population that we are going to study is divided into six compartments: potential drug users, light drug users, heavy
Abderrahim Labzai, Abdelfatah Kouidere, Bouchaib Khajji, Omar Balatif, Mostafa Rachik   +4 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

A New Mathematical Modeling with Optimal Control Strategy for the Dynamics of Population of Diabetics and Its Complications with Effect of Behavioral Factors

Journal of Applied Mathematics, 2020
We propose an optimal control strategy by conducting awareness campaigns for diabetics about the severity of complications of diabetes and the negative impact of an unbalanced lifestyle and the surrounding environment, as well as treatment and ...
Abdelfatah Kouidere, Abderrahim Labzai, Hanane Ferjouchia, Omar Balatif, Mostafa Rachik   +4 more
doaj   +1 more source