Results 101 to 110 of about 89,082 (267)

Logical Dynamics and Dynamical Systems.

open access: yes, 2018
This thesis is on information dynamics modeled using *dynamic epistemic logic* (DEL). It takes the simple perspective of identifying models with maps, which under a suitable topology may be analyzed as *topological dynamical systems*. It is composed of an introduction and six papers.
openaire   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Health Systems: A Dynamic System~benefits From System Dynamics [PDF]

open access: yesProceedings of the Winter Simulation Conference, 2005., 2006
C. Patrick Koelling, Michael J. Schwandt
openaire   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Recombinant dynamical systems

open access: yesCoRR
We describe a connectionist model that attempts to capture a notion of experience-based problem solving or task learning, whereby solutions to newly encountered problems are composed from remembered solutions to prior problems. We apply this model to the computational problem of \emph{efficient sequence generation}, a problem for which there is no ...
openaire   +2 more sources

PRODUCT DYNAMICAL SYSTEMS

open access: yesFar East Journal of Dynamical Systems, 2014
The equicontinuity, sensitivity, distality, chain transitivity, expansiveness, pseudo orbit tracing property (POTP) of the product dynamical system have been studied when the dynamical system  has these properties and vice versa.
openaire   +2 more sources

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