Results 111 to 120 of about 46,048,977 (302)
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Modular Interdependency in Complex Dynamical Systems
, 2005 Simon’s characterisation of modularity in dynamical systems describes subsystems as having dynamics that are approximately independent of those of other subsystems (in the short term). This fits with the general intuition that modules must, by definition,
Pollack, Jordan B., Watson, Richard A.
core +1 more source
Information Theory and Dynamical System Predictability
Entropy, 2011 Predicting the future state of a turbulent dynamical system such as the atmosphere has been recognized for several decades to be an essentially statistical undertaking.
R. Kleeman
semanticscholar +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Non-autonomous dynamical systems
, 2015 This review paper treats the dynamics of non-autonomous dynamical systems. To study the forwards asymptotic behaviour of a non-autonomous differential equation we need to analyse the asymptotic configurations of the non-autonomous terms present in the ...
Langa, José A. +2 more
core +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Robust Stability of Dynamical System
Engineering Transactions, 1996 A general concept of the robust stability of uncertain nonlinear dynamical systems is given. By using the method of optimal Lyapunov functions, the robust stability analysis is performed in the general case of a multidimensional system described by ...
A. Ossowski
doaj
Robust synchronization for 2-D discrete-time coupled dynamical networks [PDF]
, 2012 This is the post-print version of the Article. The official published version can be accessed from the link below - Copyright @ 2012 IEEEIn this paper, a new synchronization problem is addressed for an array of 2-D coupled dynamical networks.
Liu, X, Liang, J, Wang, Z, Louvieris, P
core +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source