Results 171 to 180 of about 89,082 (267)

Mathematical and sensitivity analysis for chemical species in multistep dynamical system: A computational study. [PDF]

Heliyon
Sultan F, Ishaq MS.
europepmc   +1 more source

Tikhonov regularization of a second order dynamical system with Hessian driven damping. [PDF]

Math Program, 2021
Boţ RI, Csetnek ER, László SC.
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Unambiguous Models and Machine Learning Strategies for Anomalous Extreme Events in Turbulent Dynamical System. [PDF]

Entropy (Basel)
Qi D.
europepmc   +1 more source

Behavioral response of population on transmissibility and saturation incidence of deadly pandemic through fractional order dynamical system. [PDF]

Results Phys, 2021
Abdul Razzaq O, Alam Khan N, Faizan M, Ara A, Ullah S.   +4 more
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Optimal Estimation of a Signal Generated Using a Dynamical System Modeled with McKean-Vlasov Stochastic Differential Equations. [PDF]

Entropy (Basel)
Dragan V, Aberkane S.
europepmc   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

TimeTeller: A tool to probe the circadian clock as a multigene dynamical system. [PDF]

PLoS Comput Biol
Vlachou D, Veretennikova M, Usselmann L, Vasilyev V, Ott S, Bjarnason GA, Dallmann R, Levi F, Rand DA.   +8 more
europepmc   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source