Results 161 to 170 of about 89,082 (267)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

The fractional soliton solutions of the dynamical system of equations for ion sound and Langmuir waves: a comparative analysis. [PDF]

Sci Rep
Faridi WA, Jhangeer A, Riaz MB, Asjad MI, Muhammad T.   +4 more
europepmc   +1 more source

Coexistence of chaotic attractor and unstable limit cycles in a 3D dynamical system. [PDF]

Open Res Eur, 2021
Constantinescu D, Tigan G, Zhang X.
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Relationship Between Intensive Passive Data Signals and Patterns of Binge-Eating Behaviors: From a Dynamical-System Approach. [PDF]

Clin Psychol Sci
Shi Q, Thornton LM, Kilshaw R, Flatt RE, Butner JE, Adamo C, Deboeck PR, Baucom BRW, Tregarthen J, Argue S, Bulik CM.   +10 more
europepmc   +1 more source

Turing instability in an economic-demographic dynamical system may lead to pattern formation on a geographical scale. [PDF]

J R Soc Interface, 2021
Zincenko A, Petrovskii S, Volpert V, Banerjee M.   +3 more
europepmc   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

Adaptive fixed-time TSM for uncertain nonlinear dynamical system under unknown disturbance. [PDF]

PLoS One
Ahmed S, Azar AT, Wang H.
europepmc   +1 more source

Single Neuronal Dynamical System in Self-Feedbacked Hopfield Networks and Its Application in Image Encryption. [PDF]

Entropy (Basel), 2021
Xu X, Chen S.
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source