Results 161 to 170 of about 170,832 (317)

Unsupervised learning of stationary and switching dynamical system models from Poisson observations. [PDF]

J Neural Eng, 2023
Song CY, Shanechi MM.
europepmc   +1 more source

Health Systems: A Dynamic System~benefits From System Dynamics [PDF]

Proceedings of the Winter Simulation Conference, 2005., 2006
C. Patrick Koelling, Michael J. Schwandt
openaire   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

On fast simulation of dynamical system with neural vector enhanced numerical solver. [PDF]

Sci Rep, 2023
Huang Z, Liang S, Zhang H, Yang H, Lin L.   +4 more
europepmc   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Resonances of the SD oscillator due to the discontinuous phase [PDF]

, 2011
Resonance phenomena of a harmonically excited system with mul-tiple potential well play an important role in nonlinear dynamics research.In this paper, we investigate the resonant behaviours of a discontinuous dynamical system with double well potential ...
Wiercigroch, Marian, Cao, Qingjie, Xiong, Yeping   +2 more
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Time Rescaling of a Primal-Dual Dynamical System with Asymptotically Vanishing Damping. [PDF]

Appl Math Optim, 2023
Hulett DA, Nguyen DK.
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Dynamical system analysis of interacting dark energy in LRS Bianchi type I cosmology. [PDF]

Sci Rep, 2023
Rathore S, Singh SS.
europepmc   +1 more source