Results 101 to 110 of about 763,790 (287)

Revisiting the impulse response creates an improved PID autotuner

Scientific Reports
Industrial practice navigates a robust controller tuning due to fairly uncertain process information. A comprehensive process identification is often avoided due to operating conditions, continuous manufacturing, etc. When process properties or operating
Robin De Keyser, Isabela R. Birs, Cristina I. Muresan, Clara M. Ionescu   +3 more
doaj   +1 more source

Spectral signature of nonequilibrium conditions

, 2011
The study of stochastic systems has received considerable interest over the years. Their dynamics can describe many equilibrium and nonequilibrium fluctuating systems.
Andrieux, David
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Selecting Optimal Long Short-Term Memory (LSTM) Architectures for Online Estimation of Mean Arterial Pressure (MAP) in Patients Undergoing General Anesthesia

Applied Sciences
In the realm of anesthetic management during surgical procedures, the reliable estimation of mean arterial pressure (MAP) is critical for ensuring patient safety and optimizing drug administration. This paper investigates the determination of the optimal
Ghada Ben Othman, Dana Copot, Erhan Yumuk, Martine Neckebroek, Clara M. Ionescu   +4 more
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Target informed client recruitment for efficient federated learning in healthcare

BMC Medical Informatics and Decision Making
Background Modern machine learning and deep learning methods have been widely incorporated in decision making processes in healthcare in the form of decision support mechanisms.
Vincent Scheltjens, Lyse Naomi Wamba Momo, Wouter Verbeke, Bart De Moor   +3 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Dynamical Systems and Topological Surgery

, 2008
In this paper we try to establish a connection between a three-dimensional Lotka--Volterra dynamical system and two-dimensional topological surgery. There are many physical phenomena exhibiting two-dimensional topological surgery through a `hole drilling'
Antoniou, S., Lambropoulou, S.
core  

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

On the Lebesgue measure of one generalised set of subsums of geometric series

Математичні Студії
In the present paper, we study a set that can be treated as a generalised set of subsums for a geometric series. This object was discovered independently in various mathematical aspects.
O. P. Makarchuk, D. M. Karvatskyi
doaj   +1 more source