Results 101 to 110 of about 174,639 (318)

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Bisimulation of Dynamical Systems

, 2004
A general notion of bisimulation is studied for dynamical systems. An algebraic characterization of bisimulation together with an algorithm for computing the maximal bisimulation relation is derived using geometric control theory. Bisimulation of dynamical systems is shown to be a concept which unifies the system-theoretic concepts of state space ...
openaire   +3 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

The 1995-2018 global evolution of the network of amicable and hostile relations among nation-states

Communications Physics, 2020
Studying the evolution of the network of amicable and hostile relations between countries allows powerful insights into global events such as the origin of wars, economy collapses, and the result of political elections.
Omid Askarisichani, Ambuj K. Singh, Francesco Bullo, Noah E. Friedkin   +3 more
doaj   +1 more source

Quantitative recurrence statistics and convergence to an extreme value distribution for non-uniformly hyperbolic dynamical systems [PDF]

, 2016
For non-uniformly hyperbolic dynamical systems we consider the time series of maxima along typical orbits. Using ideas based upon quantitative recurrence time statistics we prove convergence of the maxima (under suitable normalization) to an extreme ...
Sterk, A.E.; id_orcid, Holland, Mark P., Holland, M.P., Sterk, A.E., Rabassa, P, Sterk, AE, Rabassa, P.   +6 more
core   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Extreme value laws in dynamical systems under physical observables [PDF]

, 2012
Extreme value theory for chaotic deterministic dynamical systems is a rapidly expanding area of research. Given a system and a real function (observable) defined on its phase space, extreme value theory studies the limit probabilistic laws obeyed by ...
Holland, Mark P., Renato Vitolo, Sterk, Alef E., Sterk, Alef E.; id_orcid, Vitolo, Renato,, Henk W. Broer, Holland, Mark P.,, Sterk, Alef E.,, Rabassa, Pau,, Mark P. Holland, Alef E. Sterk, Rabassa, Pau, Pau Rabassa, Broer, Hendrik; id_orcid, Vitolo, Renato, Broer, Henk W.,, Broer, Hendrik   +16 more
core   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Preimage entropy for random dynamical systems

, 2007
In [6]. Cheng and Newhouse introduced and studied the new invariants - preimage entropies for deterministic dynamical systems. In this paper, the analogous notions, measure-theoretic preimage entropy and topological preimage entropy, are formulated for ...
Zhu, Yujun
core  

Self-protection versus fear of stricter firearm regulations: examining the drivers of firearm acquisitions in the aftermath of a mass shooting. Porfiri et al.

These data were used for information-theoretic analysis of State-level firearm acquisitions. The analysis took into consideration the location of mass shootings, media coverage, and firearm-related legal environment.
Systems Laboratory, D
core   +1 more source