Results 111 to 120 of about 174,639 (318)
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Modular Interdependency in Complex Dynamical Systems
, 2005 Simon’s characterisation of modularity in dynamical systems describes subsystems as having dynamics that are approximately independent of those of other subsystems (in the short term). This fits with the general intuition that modules must, by definition,
Pollack, Jordan B., Watson, Richard A.
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Dynamics of quantum systems [PDF]
Physical Review E, 2001 A relation between the eigenvalues of an effective Hamilton operator and the poles of the $S$ matrix is derived which holds for isolated as well as for overlapping resonance states. The system may be a many-particle quantum system with two-body forces between the constituents or it may be a quantum billiard without any two-body forces.
openaire +4 more sources
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Revisiting the impulse response creates an improved PID autotuner
Scientific ReportsIndustrial practice navigates a robust controller tuning due to fairly uncertain process information. A comprehensive process identification is often avoided due to operating conditions, continuous manufacturing, etc. When process properties or operating
Robin De Keyser +3 more
doaj +1 more source
Large deviations in non-uniformly hyperbolic dynamical systems
, 2008 The published version is located at http://fpbmonitor.com/action/displayAbstract?fromPage=online&aid=1825324&next=true&jid=ETS&volumeId=28&issueId=02We prove large deviation principles for ergodic averages of dynamical systems admitting Markov tower ...
Rey-Bellet, L, Young, LS
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Theory Reduction in Physics: A Model-Based, Dynamical Systems Approach [PDF]
, 2013 In 1973, Nickles identified two senses in which the term `reduction' is used to describe the relationship between physical theories: namely, the sense based on Nagel's seminal account of reduction in the sciences, and the sense that seeks to extract one ...
Joshua Rosaler, Rosaler, Joshua
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The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Convergence of renormalisation and rigidity of dynamical systems [PDF]
Motivated by problems in the theory of renormalisation of dynamical systems, we study the properties of Markov families and fractals defined by embedded trees. Our main results concern the classification of Ck+a structures.
Pinto, Alberto A.
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