Results 131 to 140 of about 9,197,234 (309)

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Federated Learning Under a Digital Communication Model

open access: yesIEEE Open Journal of Signal Processing
Federated learning (FL) has received significant attention recently as a topic in distributed learning. In FL, a global model is cooperatively trained by edge devices, as agents, where data is locally generated, processed, and utilized.
Pourya Behmandpoor   +2 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Hidden-like Attractors in a Class of Discontinuous Dynamical Systems

open access: yes
In continuous dynamical systems, a hidden attractor occurs when its basin of attraction does not connect with small neighborhoods of equilibria. This research aims to investigate the presence of hidden-like attractors in a class of discontinuous systems ...
Hany A. Hosham   +4 more
core   +1 more source

Health Systems: A Dynamic System~benefits From System Dynamics [PDF]

open access: yesProceedings of the Winter Simulation Conference, 2005., 2006
C. Patrick Koelling, Michael J. Schwandt
openaire   +2 more sources

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Designing a New Digital Modulator for Chaotic Secure Communication Systems Using Total

open access: yesIranian Journal of Electrical and Electronic Engineering, 2018
This paper addresses a new method for decreasing error in secure chaotic communication which utilizes an adaptive law in demodulator part. The basic tools in this process are the Total Least Square as the fundamental technique in demodulating section and
M. Evazi   +3 more
doaj  

Convergence of renormalisation and rigidity of dynamical systems [PDF]

open access: yes
Motivated by problems in the theory of renormalisation of dynamical systems, we study the properties of Markov families and fractals defined by embedded trees. Our main results concern the classification of Ck+a structures.
Pinto, Alberto A.
core  

Theory Reduction in Physics: A Model-Based, Dynamical Systems Approach [PDF]

open access: yes, 2013
In 1973, Nickles identified two senses in which the term `reduction' is used to describe the relationship between physical theories: namely, the sense based on Nagel's seminal account of reduction in the sciences, and the sense that seeks to extract one ...
Joshua Rosaler, Rosaler, Joshua
core  

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

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