Results 121 to 130 of about 174,639 (318)

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

FEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia, Anna Dósa, Asha Kiran Maddali, András Jipa, Hajnalka Laczkó‐Dobos, Péter Lőw, Gábor Juhász   +6 more
wiley   +1 more source

Target informed client recruitment for efficient federated learning in healthcare

BMC Medical Informatics and Decision Making
Background Modern machine learning and deep learning methods have been widely incorporated in decision making processes in healthcare in the form of decision support mechanisms.
Vincent Scheltjens, Lyse Naomi Wamba Momo, Wouter Verbeke, Bart De Moor   +3 more
doaj   +1 more source

Dynamical systems : control and stability

, 2015
Proceedings of the 13th Conference „Dynamical Systems - Theory and Applications" summarize 164 and the Springer Proceedings summarize 60 best papers of university teachers and students, researchers and engineers from whole the world.

core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Selecting Optimal Long Short-Term Memory (LSTM) Architectures for Online Estimation of Mean Arterial Pressure (MAP) in Patients Undergoing General Anesthesia

Applied Sciences
In the realm of anesthetic management during surgical procedures, the reliable estimation of mean arterial pressure (MAP) is critical for ensuring patient safety and optimizing drug administration. This paper investigates the determination of the optimal
Ghada Ben Othman, Dana Copot, Erhan Yumuk, Martine Neckebroek, Clara M. Ionescu   +4 more
doaj   +1 more source

Far East Journal of Dynamical Systems

The Far East Journal of Dynamical Systems is a peer-reviewed international journal, which publishes original research papers and survey articles in all aspects of Dynamical Systems.
LENCI, MARCO
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Hidden-like Attractors in a Class of Discontinuous Dynamical Systems

In continuous dynamical systems, a hidden attractor occurs when its basin of attraction does not connect with small neighborhoods of equilibria. This research aims to investigate the presence of hidden-like attractors in a class of discontinuous systems ...
Hany A. Hosham, Thoraya N. Alharthi, Mashael A. Aljohani, Eman D. Abou Elela, Nada A. Almuallem   +4 more
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

On the Lebesgue measure of one generalised set of subsums of geometric series

Математичні Студії
In the present paper, we study a set that can be treated as a generalised set of subsums for a geometric series. This object was discovered independently in various mathematical aspects.
O. P. Makarchuk, D. M. Karvatskyi
doaj   +1 more source