Results 131 to 140 of about 225,954 (249)

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Time-varying dynamic event-triggered-based prescribed-time leader-following consensus for multi-agent systems with input saturation

Meilin Li, Yue Long, Kai Zhang, Tieshan Li   +3 more
openalex   +1 more source

Dynamic Systems Analysis Report for Nuclear Fuel Recycle

, 2008
Brent Dixon, Sonny Kim, David Shropshire, Steven J. Piet, Gretchen Matthern, Bill Halsey   +5 more
openalex   +2 more sources

Neuromorphic robust framework for integrated estimation and control in dynamical systems using spiking neural networks. [PDF]

Sci Rep
Ahmadvand R, Sharif SS, Banad YM.
europepmc   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Dynamical systems theory as an organizing principle for single-cell biology. [PDF]

NPJ Syst Biol Appl
Islam S, Bhattacharya S.
europepmc   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Data assimilation with machine learning for dynamical systems: Modelling indoor ventilation

Claire E. Heaney, Jieyi Tang, Jintao Yan, Donghu Guo, Jamesson Ipock, Sanjana Kaluvakollu, Yushen Lin, Danhui Shao, Boyang Chen, Laetitia Mottet, Prashant Kumar, Christopher C. Pain   +11 more
openalex   +1 more source

Temporally-consistent koopman autoencoders for forecasting dynamical systems. [PDF]

Sci Rep
Nayak I, Chakrabarti A, Kumar M, Teixeira FL, Goswami D.   +4 more
europepmc   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source