Results 11 to 20 of about 27,598 (253)

Systems Biology - Systems Dynamics of Cytogenesis

open access: yes, 2021
Systems ...
Zeng, Xiao Xue, Zeng, (Bangzhe) Jie
openaire   +1 more source

Global entrainment of transcriptional systems to periodic inputs. [PDF]

open access: yesPLoS Computational Biology, 2010
This paper addresses the problem of providing mathematical conditions that allow one to ensure that biological networks, such as transcriptional systems, can be globally entrained to external periodic inputs.
Giovanni Russo   +2 more
doaj   +1 more source

Cellular Dynamics, a Systems Biology Bottleneck [PDF]

open access: yesTrends in Plant Science, 2019
Developing a mechanistic understanding of plant growth regulation requires studying cell division and cell expansion in addition to molecular studies. A recent time-lapse confocal microscopy study (Fox, S. et al. PLoS Biol. 2018:16;e2005952) quantifying these processes in individual cells in growing organs in combination with multiscale modeling ...
openaire   +2 more sources

Systems dynamics of biology [PDF]

open access: yesJournal of Applied Biomedicine, 2005
As more information accumulates on the detailed dynamics of life processes, emphasis on steady state behaviour gives way to the recognition that the organism is a multi-oscillator. Systems biology takes account of the controls and balances on inputs and outputs between the environment and the open system of the functioning organism. The matching of the
openaire   +1 more source

Dynamical systems, attractors, and neural circuits [version 1; referees: 3 approved]

open access: yesF1000Research, 2016
Biology is the study of dynamical systems. Yet most of us working in biology have limited pedagogical training in the theory of dynamical systems, an unfortunate historical fact that can be remedied for future generations of life scientists.
Paul Miller
doaj   +1 more source

The challenges facing systemic approaches in biology: an interview with Kunihiko Kaneko

open access: yesFrontiers in Physiology, 2011
Interviewed by Kumar Selvarajoo and Masa Tsuchiya at Institute for Advanced Biosciences, Keio University, Japan, I discuss my approach to biology, what I call complex-systems biology.
Kunihiko eKaneko
doaj   +1 more source

Structural Identifiability of Dynamic Systems Biology Models

open access: yesPLOS Computational Biology, 2016
A powerful way of gaining insight into biological systems is by creating a nonlinear differential equation model, which usually contains many unknown parameters. Such a model is called structurally identifiable if it is possible to determine the values of its parameters from measurements of the model outputs.
Alejandro Fernández Villaverde   +2 more
openaire   +6 more sources

Dysregulated biodynamics in metabolic attractor systems precede the emergence of amyotrophic lateral sclerosis.

open access: yesPLoS Computational Biology, 2020
Evolutionarily conserved mechanisms maintain homeostasis of essential elements, and are believed to be highly time-variant. However, current approaches measure elemental biomarkers at a few discrete time-points, ignoring complex higher-order dynamical ...
Paul Curtin   +9 more
doaj   +1 more source

Editorial: Quantitative Biology: Dynamics of Living Systems [PDF]

open access: yesFrontiers in Physiology, 2016
With the emergence of Systems Biology, there is a greater realization that the whole behavior of a living system may not be simply described as the sum of its elements. To represent a living system using mathematical principles, practical quantities with units are required.
Hiroi, Noriko   +2 more
openaire   +2 more sources

Architectural Principles for Characterizing the Performance of Antithetic Integral Feedback Networks

open access: yesiScience, 2019
Summary: As we begin to design increasingly complex synthetic biomolecular systems, it is essential to develop rational design methodologies that yield predictable circuit performance.
Noah Olsman   +2 more
doaj   +1 more source

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