Results 31 to 40 of about 139,067 (282)

Parameter inference in dynamical systems with co-dimension 1 bifurcations [PDF]

open access: yesRoyal Society Open Science, 2019
Dynamical systems with intricate behaviour are all-pervasive in biology. Many of the most interesting biological processes indicate the presence of bifurcations, i.e.
Elisabeth Roesch, Michael P. H. Stumpf
doaj   +1 more source

Delegated causality of complex systems

open access: yes, 2018
A notion of delegated causality is introduced here. This subtle kind of causality is dual to interventional causality. Delegated causality elucidates the causal role of dynamical systems at the “edge of chaos”, explicates evident cases of downward ...
Vidunas, R.
core   +1 more source

Chemical reaction systems with toric steady states [PDF]

open access: yes, 2011
Mass-action chemical reaction systems are frequently used in Computational Biology. The corresponding polynomial dynamical systems are often large (consisting of tens or even hundreds of ordinary differential equations) and poorly parametrized (due to ...
Conradi, Carsten   +3 more
core   +3 more sources

Foraging Dynamics and Entropy Production in a Simulated Proto-Cell

open access: yesEntropy, 2022
All organisms depend on a supply of energetic resources to power behavior and the irreversible entropy-producing processes that sustain them. Dissipative structure theory has often been a source of inspiration for better understanding the thermodynamics ...
Benjamin De Bari   +2 more
doaj   +1 more source

Two Faces of NOTCH1 in Childhood Lymphoblastic T‐Cell Neoplasia: Prognostic Divergence of Mutational and Structural Aberrations

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider   +4 more
wiley   +1 more source

Simulation-based model selection for dynamical systems in systems and population biology [PDF]

open access: yesBioinformatics, 2009
Abstract Motivation: Computer simulations have become an important tool across the biomedical sciences and beyond. For many important problems several different models or hypotheses exist and choosing which one best describes reality or observed data is not straightforward. We therefore require suitable statistical tools that allow us to
Toni, T, Stumpf, MPH
openaire   +4 more sources

Effects of the Fluid Replacement Method During Online Hemodiafiltration on the Solute Removal Performance and Biocompatibility Using the Asymmetric Cellulose Triacetate Membrane

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Pre‐dilution online hemodiafiltration (Pre‐HDF) is predominantly used in Japan, whereas post‐dilution online HDF (Post‐HDF) is more common in Europe. An asymmetric cellulose triacetate (ATA) membrane may improve biocompatibility.
Kenji Sakurai   +4 more
wiley   +1 more source

Using both qualitative and quantitative data in parameter identification for systems biology models

open access: yesNature Communications, 2018
Much of the data generated in biology is qualitative, but exploiting such data to inform models of biological systems remains a challenge. Here, the authors demonstrate an approach that allows use of both quantitative and qualitative data for ...
Eshan D. Mitra   +3 more
doaj   +1 more source

Synthetic Biology: opportunities for Chilean bioindustry and education

open access: yesBiological Research, 2013
In an age of pressing challenges for sustainable production of energy and food, the new field of Synthetic Biology has emerged as a promising approach to engineer biological systems.
Fernán Federici   +4 more
doaj   +1 more source

On Kinetic Equations Modeling Evolution of Systems in Mathematical Biology

open access: yes, 2013
We develop a rigorous formalism for the description of the kinetic evolution of interacting entities modeling systems in mathematical biology within the framework of the evolution of marginal observables.
Fedchun, Yu. Yu., Gerasimenko, V. I.
core   +1 more source

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