Results 51 to 60 of about 139,067 (282)

Molecular dynamics recipes for genome research [PDF]

open access: yes, 2017
Molecular dynamics (MD) simulation allows one to predict the time evolution of a system of interacting particles. It is widely used in physics, chemistry and biology to address specific questions about the structural properties and dynamical mechanisms ...
Biagini, Tommaso   +8 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Recent applications of fractional calculus to science and engineering

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2003
This paper deals with recent applications of fractional calculus to dynamical systems in control theory, electrical circuits with fractance, generalized voltage divider, viscoelasticity, fractional-order multipoles in electromagnetism, electrochemistry ...
Lokenath Debnath
doaj   +1 more source

A discrete dynamical system arising in molecular biology

open access: yesDiscrete and Continuous Dynamical Systems - B, 2012
SELEX (Systematic Evolution of Ligands by EXponential Enrichment) is an iterative separation process by which a pool of nucleic acids that bind with varying specificities to a fixed target molecule or a fixed mixture of target molecules, i.e., single or multiple targets, can be separated into one or more pools of pure nucleic acids.
Howard A. Levine   +2 more
openaire   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

How to make epidemiological training infectious. [PDF]

open access: yesPLoS Biology, 2012
Modern infectious disease epidemiology builds on two independently developed fields: classical epidemiology and dynamical epidemiology. Over the past decade, integration of the two fields has increased in research practice, but training options within ...
Steve E Bellan   +4 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Breaking reflection symmetry: evolving long dynamical cycles in Boolean systems

open access: yesNew Journal of Physics
In interacting dynamical systems, specific local interaction rules for system components give rise to diverse and complex global dynamics. Long dynamical cycles are a key feature of many natural interacting systems, especially in biology.
Mathieu Ouellet   +5 more
doaj   +1 more source

Dynamics of Unperturbed and Noisy Generalized Boolean Networks

open access: yes, 2009
For years, we have been building models of gene regulatory networks, where recent advances in molecular biology shed some light on new structural and dynamical properties of such highly complex systems.
Darabos, Christian   +2 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

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